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Chemical Structure| 184904-70-9 Chemical Structure| 184904-70-9

Structure of 184904-70-9

Chemical Structure| 184904-70-9

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Product Details of [ 184904-70-9 ]

CAS No. :184904-70-9
Formula : C11H9NO4
M.W : 219.19
SMILES Code : O=C(C1=CC2=C(N(C)C(C2=O)=O)C=C1)OC

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Application In Synthesis of [ 184904-70-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 184904-70-9 ]

[ 184904-70-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 128742-76-7 ]
  • [ 184904-70-9 ]
YieldReaction ConditionsOperation in experiment
89% With N-iodo-succinimide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; at 15 - 25℃; for 6h; General procedure: A 5 mL round bottom flask was charged with 0.1 g of indole and 2.0 mL of DMSO. To the resultant solution was added NIS (1.2 equiv)/IBX (3.0 equiv), and the reaction mixture was stirred at 20 ± 5 C.Progress of the reaction was monitored by TLC (thin layer chromatography) analysis. After completion ofthe reaction, the reaction mixture was diluted with 20 mL of ethyl acetate, and the organic phase was washed with saturated solution of Na2S2O3 followed by brine, and then dried over anhyd. Na2SO4. Subsequently, the extract was stripped off the solvent under reduced pressure, and the product was isolated by silica gel column chromatography.
 

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