Alternatived Products of [ 18706-26-8 ]
Product Details of [ 18706-26-8 ]
CAS No. : | 18706-26-8 |
MDL No. : | MFCD12197299 |
Formula : |
C11H5F3N2
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
222.17
|
Pubchem ID : | - |
Synonyms : |
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Safety of [ 18706-26-8 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 18706-26-8 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 18706-26-8 ]
- 1
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copper(l) cyanide
[ No CAS ]
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[ 18706-25-7 ]
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[ 18706-26-8 ]
Yield | Reaction Conditions | Operation in experiment |
21 g |
With potassium carbonate In N,N-dimethyl-formamide Reflux; |
1.2 (2) Synthesis of 2-(trifluoromethyl)-4-cyanoquinoline
28 g of 4-bromo-2-(trifluoromethyl)quinoline was added to 280 ml of N,N-dimethylformamide.Add 16g of anhydrous potassium carbonate, and then add 21g of cuprous cyanide.Heated to reflux overnight, cooled to room temperature and concentrated.Add water and dichloromethane, extract the liquid, collect the organic phase, and separate the liquid.Dry, concentrated,The residue was separated on a silica gel column to give 21 g of 2-(trifluoromethyl)-4-cyanoquinoline. |
- 2
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[ 1701-18-4 ]
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[ 18706-26-8 ]