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Chemical Structure| 1871-57-4 Chemical Structure| 1871-57-4

Structure of 1871-57-4

Chemical Structure| 1871-57-4

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Product Details of [ 1871-57-4 ]

CAS No. :1871-57-4
Formula : C4H6Cl2
M.W : 125.00
SMILES Code : C=C(CCl)CCl
MDL No. :MFCD00000952
InChI Key :XJFZOSUFGSANIF-UHFFFAOYSA-N
Pubchem ID :15859

Safety of [ 1871-57-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H226-H301-H315-H319-H330-H335
Precautionary Statements:P210-P301+P310+P330-P302+P352-P304+P340+P310-P305+P351+P338
Class:3(6.1)
UN#:1992
Packing Group:

Application In Synthesis of [ 1871-57-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1871-57-4 ]

[ 1871-57-4 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 1871-57-4 ]
  • [ 3513-81-3 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In water; A. Preparation of 2-methylene-1,3-propanediol A mixture of 100 g of 2-methylene-1,3-dichloropropane and 121.62 of potassium carbonate in 800 ml of water was stirred and refluxed for 40 hours. The reaction mixture was concentrated by evaporation under reduced pressure to give a thick slurry which was extracted with four 100-ml portions of ethyl acetate. The extracts were filtered, combined, dried over Na2 SO4 and concentrated under reduced pressure to an oil. Distillation of the oil gave 58.3 g of 2-methylene-1,3-propanediol, b.p. 68°-72°/0.24-0.25 mm Hg.
  • 2
  • [ 3513-81-3 ]
  • [ 1871-57-4 ]
YieldReaction ConditionsOperation in experiment
32% With pyridine; thionyl chloride; In dichloromethane; for 3h;Reflux; Example 7; 5-Cvclopropyl-2-(4-fluorophenyl)-6-rr(2-hvdroxy-1 ,2-oxaborolan-4- yl)methyll(methylsulfonyl)aminol-N-methyl-1 -benzofuran-3-carboxamide Step 1 : 3-chloro-2-(chloromethyl)prop-1 -eneA solution of thionyl chloride (290 g, 1 19 mmol) in DCM (200 mL) was added dropwise into a mixture of 2-methylenepropane-1 ,3-diol (88 g, 1 mol), dry pyridine (150 mL), and dry DCM (100 mL). The reaction mixture was heated to reflux with stirring for 3 hours and then allowed to stand overnight. The mixture was cooled to room temperature and poured into ice. The solution was neutralized with solid sodium bicarbonate and then extracted with diethyl ether(3 <0.6 L) followed by washing the ether extracts with dilute sulfuric acid. The combined organic layers were dried with anhydrous sodium sulfate, filtered, and concentrated in vacuo to give a residue which was fractionated to give 3-chloro-2- (chloromethyl)prop-l -ene (40.1 g, 32percent) as a colorless oil.
  • 3
  • [ 1871-57-4 ]
  • [ 119838-38-9 ]
  • (S)-2-tert-Butyl-5-(2-chloromethyl-allyl)-3-methyl-4-oxo-imidazolidine-1-carboxylic acid tert-butyl ester [ No CAS ]
 

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