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Chemical Structure| 188923-20-8 Chemical Structure| 188923-20-8

Structure of 188923-20-8

Chemical Structure| 188923-20-8

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Product Details of [ 188923-20-8 ]

CAS No. :188923-20-8
Formula : C7H15NO3
M.W : 161.20
SMILES Code : O[C@H]1COC(C)(C)OC[C@@H]1N
MDL No. :MFCD09951874

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Application In Synthesis of [ 188923-20-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 188923-20-8 ]

[ 188923-20-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 57280-22-5 ]
  • [ 188923-20-8 ]
YieldReaction ConditionsOperation in experiment
87% With ammonia; In water; A. A steel bomb was charged with liquid ammonia (60 ml) with cooling in an isopropanol-dry ice bath maintained at -70 C. The epoxide (III) (21.46 g, 0.15 mole) was added to it, followed by water (2.70 ml, 0.15 mole). The bomb was sealed and, then, heated in an oil bath at 120 for 4 hr. The bomb was cooled, opened and the ammonia was allowed to evaporate. The crude residue was triturated with ether, chilled, and the crystalline product was isolated by filtration. The amine (IV) was obtained as white prisms. (18.78 g, yield 87%). m.p. 81.5-82.5.
 

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