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Chemical Structure| 190900-20-0 Chemical Structure| 190900-20-0

Structure of 190900-20-0

Chemical Structure| 190900-20-0

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Product Details of [ 190900-20-0 ]

CAS No. :190900-20-0
Formula : C7H14N2O3
M.W : 174.20
SMILES Code : O=C1NCCNCC1.CC(O)=O
MDL No. :MFCD08262831

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Application In Synthesis of [ 190900-20-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 190900-20-0 ]

[ 190900-20-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 190900-20-0 ]
  • [ 24424-99-5 ]
  • [ 190900-21-1 ]
YieldReaction ConditionsOperation in experiment
219 mg (89%) With sodium hydroxide; sodium chloride; In chloroform; Step B 1-(tert-Butoxycarbonyl)hexahydro-(5H)-1,4-diazepin-5-one A mixture of hexahydro-(5H)-1,4-diazepin-5-one acetic acid salt (200 mg, 1.15 mmol), di-tert-butyldicarbonate (277 mg, 1.27 mmol) and sodium chloride (460 mg, 7.93 mmol) in 2.0 mL of chloroform was stirred and 2.5 N aqueous sodium hydroxide (460 uL, 1.15 mmol) was added. The mixture was heated to reflux for 4 h, and then extracted with 3*10 mL of-ethyl acetate. The combined ethyl acetate extracts were dried over anhydrous sodium sulfate, decanted and evaporated in vacuo to give 219 mg (89percent) of 1-(tert-butoxycarbonyl)hexahydro-(5H)-1,4-diazepin-5-one as a white solid. 1 H NMR (400 MHz, CD3 OD): delta3.60-3.53 (m, 4H), 3.28-3.25 (m, 2H), 2.61-2.56 (m, 2H), 1.47 (s, 9H). Mass spectrum: m/z=215 (M+1, 100percent). Anal. calcd for C10 H18 N2 O3: C, 56.32; H, 8.04; N, 13.14. Found: C, 55.92; H, 8.48; N, 13.00.
  • 2
  • [ 55186-89-5 ]
  • [ 190900-20-0 ]
 

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