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Chemical Structure| 19115-29-8 Chemical Structure| 19115-29-8

Structure of 19115-29-8

Chemical Structure| 19115-29-8

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Product Details of [ 19115-29-8 ]

CAS No. :19115-29-8
Formula : C9H7ClO
M.W : 166.60
SMILES Code : C#CC(C1=CC=CC=C1Cl)O
MDL No. :MFCD09032693

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Application In Synthesis of [ 19115-29-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 19115-29-8 ]

[ 19115-29-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 19115-29-8 ]
  • [ 1794-45-2 ]
YieldReaction ConditionsOperation in experiment
80% With phosphonic Acid; In dichloromethane; water; at 110℃; for 2h;Inert atmosphere; Schlenk technique; Sealed tube; General procedure: Typical procedure: propargyl alcohols (0.2 mmol), H3PO3 50 wt% aqueous solution (0.3 mmol), CH2Cl2 (0.5 mL) were placed in10 mL sealed Schlenk tube under N2 atmosphere, then stirred at 110 C for 2 h and monitored by GC or GC-MS or TLC. After completionof the reaction, the mixture was cooled to room temperature, washed with saturated Na2CO3 solution, then extracted three times with CH2Cl2. The combined organic layer was dried with anhydrous Na2SO4, subjected to filtration, and concentrated in vacuo.The residue was purified by column chromatography on silica geland eluted with petroleum ether/ethyl acetate to afford the pure products.
 

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