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Chemical Structure| 192182-56-2 Chemical Structure| 192182-56-2

Structure of 192182-56-2

Chemical Structure| 192182-56-2

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Product Details of [ 192182-56-2 ]

CAS No. :192182-56-2
Formula : C9H8BNO2
M.W : 172.98
SMILES Code : OB(C1=CN=CC2=C1C=CC=C2)O
MDL No. :MFCD03412093
InChI Key :GDTOUTKTCGPAGY-UHFFFAOYSA-N
Pubchem ID :3761204

Safety of [ 192182-56-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 192182-56-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 192182-56-2 ]

[ 192182-56-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 877265-23-1 ]
  • [ 192182-56-2 ]
  • [ 877264-82-9 ]
  • 2
  • [ 1246765-38-7 ]
  • [ 192182-56-2 ]
  • 6-(isoquinolin-4-yl)-3,4-dihydroquinazolin-2(1H)-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
63% With tetrakis(triphenylphosphine) palladium(0); sodium carbonate; In 1,2-dimethoxyethane; water;Inert atmosphere; Reflux; General procedure: Heteroarylboronic acid (1.3 equivalents), aryl bromide (1 equivalent), and tetrakis(triphenylphosphine) palladium(0) (5mol %) were suspended in DME to give a 0.07-0.1M solution of boronic acid under nitrogen atmosphere. A 0.5M aqueous solution of sodium carbonate (6 equivalents) was added. The mixture was refluxed for 3.5-14h, cooled to room temperature, diluted with water and extracted several times with ethyl acetate. The combined extracts were dried over anhydrous MgSO4, concentrated and purified by flash chromatography and were if necessary recrystallized.
 

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[ 192182-56-2 ]

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