Home Cart Sign in  
Chemical Structure| 19482-17-8 Chemical Structure| 19482-17-8

Structure of 19482-17-8

Chemical Structure| 19482-17-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 19482-17-8 ]

CAS No. :19482-17-8
Formula : C13H11Cl
M.W : 202.68
SMILES Code : CC1=CC=C(Cl)C=C1C2=CC=CC=C2
MDL No. :MFCD14701662
Boiling Point : No data available

Safety of [ 19482-17-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 19482-17-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 19482-17-8 ]

[ 19482-17-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 27139-97-5 ]
  • [ 98-80-6 ]
  • [ 19482-17-8 ]
YieldReaction ConditionsOperation in experiment
94% With palladium diacetate; potassium carbonate; triphenylphosphine; In tetrahydrofuran; water; at 80℃; for 18h;Inert atmosphere; A 12 mL vial equipped with a magnetic stir bar was charged with 2-bromo-4-chloro methylbenzene (357.3 mg, 1.74 mmol). To this vial was added phenyl boronic acid (233 mg, 1.91 mmol), Pd(OAc)2 (19.5 mg, 0.09 mmol), P(Ph)3 (91.2 mg, 0.35 mmol), and K2 C03 (480 mg, 3.58 mmol). The vial was flushed with nitrogen and evacuated 3 times. A 10:1 mixture of anhydrous THF:H20 was then added by syringe. The resulting mixture was heated at 80 °C for 18 hours. The reaction was then cooled to rt whereupon 5 mL HzO was added. The reaction was extracted with EtOAc (3 x 10 mL) and the combined organic layers were dried over Na2 S04, filtered and concentrated under reduced pressure to yield an oil. The oil was purified using a 12 g ISCO Si02 column eluting with pure hexanes over a 30 minute period. The desired fractions were combinedand concentrated under reduced pressure to yield 5-chloro-2-methyl-1,1'-biphenyl as a clear oil(332 mg, 94percent yield). 1H NMR (400 MHz, Chloroform-d) 8 7.37-7.30 (m, 2H), 7.30-7.24 (m,1H), 7.23-7.18 (m, 2H), 7.16-7.09 (m, 3H), 2.14 (s, 3H).
 

Historical Records

Technical Information

Categories