Alternatived Products of [ 19643-45-9 ]
Product Details of [ 19643-45-9 ]
CAS No. : | 19643-45-9 |
MDL No. : | MFCD00016365 |
Formula : |
C6H2Br2O2
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
265.89
|
Pubchem ID : | - |
Synonyms : |
|
Application In Synthesis of [ 19643-45-9 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 19643-45-9 ]
- 1
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[ 344-20-7 ]
-
[ 19643-45-9 ]
Yield | Reaction Conditions | Operation in experiment |
|
With nitric acid |
|
- 2
-
[ 19643-45-9 ]
-
[ 537-45-1 ]
Yield | Reaction Conditions | Operation in experiment |
|
With sodium hypochlorite; ammonia |
|
- 3
-
[ 5324-13-0 ]
-
[ 19643-45-9 ]
- 4
-
[ 118-79-6 ]
-
[ 19643-45-9 ]
Yield | Reaction Conditions | Operation in experiment |
87% |
With perchloric acid; lead dioxide In acetic acid at 25℃; |
|
85% |
With lead dioxide In perchloric acid; acetic acid for 0.166667h; |
|
61% |
With periodic acid In water; acetonitrile at 80℃; for 6h; |
|
50% |
With cerium (IV) sulfate In water; acetonitrile |
|
|
With nitric acid |
|
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With chromium(VI) oxide; acetic acid |
|
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With lead(IV) acetate In acetic acid |
|
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With periodic acid In acetonitrile |
|
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With oxone; mer-[(2,2':6',2''-terpyridine)trichloroiron(III)] In aq. phosphate buffer; acetonitrile for 0.5h; |
Assay for TrBP degradation
A 10-mL aliquot of 0.02 M NaH2PO4/Na2HPO4 buffer (pH 4-8) was placed in a 50-mL Erlenmeyer flask and a 50 L aliquot of0.01 M TrBP in acetonitrile was then added to the solution. Aqueous catalysts were added to be produced concentrations of 0.1-10 M,and a 0.1 mL aliquot of 0.1 M KHSO5or H2O2 was then added to the mixture to start the reaction. After shaking for 30 min, a 1 mL aliquot of the reaction mixture was placed in a glass vial, and 0.5 mL2-propanol was then added. A 20 L aliquot of the mixture was injected into a PU980-type HPLC pumping system (JASCO) to ana-lyze the remaining TrBP in the reaction mixtures. The mobile phase was a mixture of methanol and water (78:22 in volume), which was acidified with aqueous 0.08% H3PO4, and the stationary phase was a COSMOSIL 5C18-AR-II column (4.6 × 250 nm). The flow rate of the eluent, the column temperature and the detection wavelength were set at 1.0 mL min-1, 50C and 290 nm, respectively.The Br-that is released as a result of the oxidation was analyzed by an ion chromatography (Dionex IC-120 type, Thermo-Fishers) with conductivity detection. The mobile phase was an aqueous solution of 2.7 mM Na2CO3/0.3 mM NaHCO3, and the separation column was an IonPacAS12A analytical column(4 × 200 mm, Thermo-Fishers) with an IonPacAG12A guard column(4 × 50 mm). The flow rate and column oven temperature were set at 1.5 mL min-1and 35C, respectively. To evaluate the percent mineralization to CO2, the concentration of total organic carbon(TOC) in the reaction mixture was analyzed before and after the reaction using a TOC-V CSH type analyzer (Shimadzu). In this test,a stock solution of 0.01 M TrBP was prepared using aqueous 0.01 MNaOH |
|
With dihydrogen peroxide; {5'-d(GAGTTCCTGGACGACATCAGGAAGGTG)-3'}*{3'-d(CACCTTCCTGATGTCGTCCAGGAACTC)-5'} In aq. phosphate buffer at 25℃; Enzymatic reaction; |
|
Reference:
[1]Omura, Kanji
[Synthesis, 1998, # 8, p. 1145 - 1148]
[2]Feng, Yu; Liu, Jun; Carrasco, Yazmin P.; MacMillan, John B.; De Brabander, Jef K.
[Journal of the American Chemical Society, 2016, vol. 138, # 22, p. 7130 - 7142]
[3]Inman, Martyn; Moody, Christopher J.
[Journal of Organic Chemistry, 2010, vol. 75, # 17, p. 6023 - 6026]
[4]Gopinathan, M. B.; Bhatt, M. Vivekananda
[Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1981, vol. 20, # 1, p. 71 - 72]
[5]Levy; Schultz,G.
[Justus Liebigs Annalen der Chemie, 1881, vol. 210, p. 160]
Hodgson; Nixon
[Journal of the Chemical Society, 1930, p. 1085]
[6]Hunter; Morse
[Journal of the American Chemical Society, 1933, vol. 55, p. 3701,3704]
[7]Wessely,F. et al.
[Monatshefte fur Chemie, 1963, vol. 94, p. 227 - 242]
[8]Perumal,P.T.; Bhatt,M.V.
[Synthesis, 1979, p. 205 - 206]
[9]Igarashi, Mami; Zhu, Qianqian; Sasaki, Masahide; Kodama, Ritsu; Oda, Kohki; Fukushima, Masami
[Journal of Molecular Catalysis A: Chemical, 2016, vol. 413, p. 100 - 106]
[10]Chen, Shun-Fa; Liu, Xi-Chun; Xu, Jia-Kun; Li, Lianzhi; Lang, Jia-Jia; Wen, Ge-Bo; Lin, Ying-Wu
[Inorganic Chemistry, 2021, vol. 60, # 4, p. 2839 - 2845]
- 5
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[ 19643-45-9 ]
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[ 19391-35-6 ]
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(S)-3-[4-(5-Bromo-3,6-dioxo-cyclohexa-1,4-dienyloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid benzyl ester
[ No CAS ]
- 6
-
[ 98-22-6 ]
-
[ 38475-55-7 ]
-
[ 19643-45-9 ]
-
[ 110190-11-9 ]
- 7
-
[ 3337-62-0 ]
-
[ 19643-45-9 ]
- 8
-
[ 98-22-6 ]
-
[ 19643-45-9 ]
- 9
-
[ 344-20-7 ]
-
[ 7697-37-2 ]
-
[ 19643-45-9 ]
- 10
-
[ 5324-13-0 ]
-
[ 7697-37-2 ]
-
[ 19643-45-9 ]
- 11
-
[ 19643-45-9 ]
-
[ 7664-41-7 ]
-
[ 537-45-1 ]
- 12
-
[ 19643-45-9 ]
-
[ 56-40-6 ]
-
[ 537-45-1 ]
- 13
-
[ 118-79-6 ]
-
[ 19643-45-9 ]
-
C6H5Br3O2
[ No CAS ]
-
C6H3BrO3
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
With oxone; mer-[(2,2':6',2''-terpyridine)trichloroiron(III)] In aq. phosphate buffer; acetonitrile at 20℃; for 0.0166667h; |
Assay for TrBP degradation
General procedure: A 10-mL aliquot of 0.02 M NaH2PO4/Na2HPO4 buffer (pH 4-8) was placed in a 50-mL Erlenmeyer flask and a 50 L aliquot of0.01 M TrBP in acetonitrile was then added to the solution. Aqueous catalysts were added to be produced concentrations of 0.1-10 M,and a 0.1 mL aliquot of 0.1 M KHSO5or H2O2 was then added to the mixture to start the reaction. After shaking for 30 min, a 1 mL aliquot of the reaction mixture was placed in a glass vial, and 0.5 mL2-propanol was then added. A 20 L aliquot of the mixture was injected into a PU980-type HPLC pumping system (JASCO) to ana-lyze the remaining TrBP in the reaction mixtures. The mobile phase was a mixture of methanol and water (78:22 in volume), which was acidified with aqueous 0.08% H3PO4, and the stationary phase was a COSMOSIL 5C18-AR-II column (4.6 × 250 nm). The flow rate of the eluent, the column temperature and the detection wavelength were set at 1.0 mL min-1, 50C and 290 nm, respectively.The Br-that is released as a result of the oxidation was analyzed by an ion chromatography (Dionex IC-120 type, Thermo-Fishers) with conductivity detection. The mobile phase was an aqueous solution of 2.7 mM Na2CO3/0.3 mM NaHCO3, and the separation column was an IonPacAS12A analytical column(4 × 200 mm, Thermo-Fishers) with an IonPacAG12A guard column(4 × 50 mm). The flow rate and column oven temperature were set at 1.5 mL min-1and 35C, respectively. To evaluate the percent mineralization to CO2, the concentration of total organic carbon(TOC) in the reaction mixture was analyzed before and after the reaction using a TOC-V CSH type analyzer (Shimadzu). In this test,a stock solution of 0.01 M TrBP was prepared using aqueous 0.01 MNaOH |
- 14
-
[ 17216-62-5 ]
-
[ 19643-45-9 ]
-
C14H11Br2NO5
[ No CAS ]
-
C14H11Br2NO5
[ No CAS ]
- 15
-
[ 10203-58-4 ]
-
[ 19643-45-9 ]
-
C15H16Br2O5
[ No CAS ]