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Chemical Structure| 197079-01-9 Chemical Structure| 197079-01-9

Structure of 197079-01-9

Chemical Structure| 197079-01-9

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Product Details of [ 197079-01-9 ]

CAS No. :197079-01-9
Formula : C7H9N3O
M.W : 151.17
SMILES Code : O=C(NN)C1=C(C)N=CC=C1
MDL No. :MFCD02068312

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Application In Synthesis of [ 197079-01-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 197079-01-9 ]

[ 197079-01-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1721-26-2 ]
  • [ 197079-01-9 ]
YieldReaction ConditionsOperation in experiment
98% With hydrazine hydrate; In ethanol; for 72h;Reflux; Inert atmosphere; To a solution of <strong>[1721-26-2]ethyl 2-methylnicotinate</strong> (500 mg, 3.0 mmol) in EtOH (2.3 mL) was added hydrazine monohydrate (0.3 mL, 6.1 mmol). The reaction mixture was heated at reflux for 3 days and then concentrated to afford the desired product as a beige solid (450 mg, 98percent). MS (ESI): mass calcd. for C7H9N3O, 151.1; m/z found, 152.1 [M+H]+. 1H NMR (500 MHz, DMSO-d6) delta 9.57 (br s, 1H), 8.49 (dd, J=4.9, 1.8 Hz, 1H), 7.66 (dd, J=7.7, 1.7 Hz, 1H), 7.26 (ddd, J=7.7, 4.9, 0.5 Hz, 1H), 4.85-4.05 (bs, 2H), 2.50 (d, J=4.1 Hz, 3H).
 

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