Home Cart Sign in  
Chemical Structure| 490-79-9 Chemical Structure| 490-79-9
Chemical Structure| 490-79-9

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

Gentisic acid is a natural product isolated and purified from the roots of Gentiana scabra Bunge.

Synonyms: Gentisic Acid; NSC 78825; NSC 49098

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Product Citations      Show More

Berrow, Stuart R ; Raistrick, Thomas ; Mandle, Richard J ; Gleeson, Helen F ;

Abstract: The observation of auxetic behaviour (i.e. negative Poisson’s ratio) in liquid crystal elastomers (LCEs) presents an exciting opportunity to explore application areas previously inaccessible to LCEs. Since its initial discovery, research has focused on improving understanding of the underpinning physics that drives the auxetic response, the structure-property relationships that enable the response to be tuned, and LCE properties such as the refractive index. However, the auxetic LCE materials reported to date have made use of either mechanical strain during fabrication, or unreactive ‘templates’ to stabilize the nematic ordering in the precursors. The latter approach provides excellent monodomain films, but there is unavoidable anisotropic shrinkage of the LCE. Both processes previously employed create complications towards manufacturing and scale-up. In this article, we report the first example of an auxetic LCE synthesized through surface alignment without the use of a non-reactive ‘template’ and thus without the need for a washout. The LCE includes both terminally and laterally attached mesogens, presents an auxetic threshold of 76% strain, and displays a comparable dependence of auxetic behaviour on its glass transition temperature as that reported in the literature. This work presents an exciting milestone in the journey towards realizing applications for auxetic LCEs.

Keywords: Liquid crystal elastomer ; Auxetic ; Mechanical metamaterials ; Elastomer ; Network

Purchased from AmBeed: ; ;

Hassan, Sara A ; Zaater, Marwa A ; Abdel-Rahman, Islam M ; Ibrahim, Elsayed A ; El Kerdawy, Ahmed M ; Abouelmagd, Sara A

Abstract: The development of new forms of existing APIs with enhanced physicochemical properties is critical for improving their therapeutic potential. In this context, ionic liquids (ILs) and deep eutectic solvents (DESs) have gained significant attention in recent years due to their unique properties and potential for solubility enhancement. In this study, we explore the role of different counterparts in the formation of IL/DESs with piperine (PI), a poorly water-soluble drug. After screening a library of fourteen counterpart molecules, ten liquid PI-counterpart systems were developed and investigated. Thermal analysis confirmed the formation of IL/DES, while computational and spectroscopic studies revealed that hydrogen bonding played a crucial role in the interaction between PI and the counterparts, confirming DES formation. The solubility enhancement of PI in these systems ranged from ∼ 36 % to 294 %, with PI-Oxalic acid (OA) exhibiting the highest saturation solubility (49.71 μg/mL) and PI-Ibuprofen (IB) the lowest (17.23 μg/mL). The presence of hydrogen bonding groups in counterparts was key to successful DES formation. A negative correlation was observed between solubility and logP (r =  − 0.75, p* = 0.0129), while a positive correlation was found between solubility and normalized polar surface area (PSA) (r = 0.68, p* = 0.029). PI-OA and PI-IB were located at the extreme ends of these regression lines, further validating the relationship between these properties and solubility enhancement. These findings highlight essential aspects of rational IL/DES design, optimizing their properties for broader applications.

Purchased from AmBeed: ;

Alternative Products

Product Details of 2,5-dihydroxybenzoic acid

CAS No. :490-79-9
Formula : C7H6O4
M.W : 154.12
SMILES Code : OC(=O)C1=C(O)C=CC(O)=C1
Synonyms :
Gentisic Acid; NSC 78825; NSC 49098
MDL No. :MFCD00002460
InChI Key :WXTMDXOMEHJXQO-UHFFFAOYSA-N
Pubchem ID :3469

Safety of 2,5-dihydroxybenzoic acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 2,5-dihydroxybenzoic acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 490-79-9 ]
  • Downstream synthetic route of [ 490-79-9 ]

[ 490-79-9 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 490-79-9 ]
  • [ 3786-46-7 ]
References: [1] Monatshefte fuer Chemie, 1913, vol. 34, p. 919.
[2] Monatshefte fuer Chemie, 1913, vol. 34, p. 919.
  • 2
  • [ 490-79-9 ]
  • [ 67127-91-7 ]
References: [1] Journal of Organic Chemistry, 2004, vol. 69, # 10, p. 3530 - 3537.
[2] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981, p. 2570 - 2576.
 

Historical Records

Categories