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Chemical Structure| 530-55-2 Chemical Structure| 530-55-2
Chemical Structure| 530-55-2

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2,6-Dimethoxy-1,4-benzoquinone exhibits strong antibacterial activities against S. pyogenes, S. mitis, and S. mutans with MIC values of 7.8, 7.8, and 15.6 ug/mL, and MBC values of 7.8, 7.8, and 31.2 ug/mL respectively. It also produces genotoxic effects in patients taking dimethophrine, it's a natural product isolated and purified from the barks of Liriodendron tulipifera.

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Product Details of 2,6-Dimethoxy-1,4-benzoquinone

CAS No. :530-55-2
Formula : C8H8O4
M.W : 168.15
SMILES Code : O=C1C(OC)=CC(C=C1OC)=O
MDL No. :MFCD00016368
InChI Key :OLBNOBQOQZRLMP-UHFFFAOYSA-N
Pubchem ID :68262

Safety of 2,6-Dimethoxy-1,4-benzoquinone

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Application In Synthesis of 2,6-Dimethoxy-1,4-benzoquinone

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 530-55-2 ]

[ 530-55-2 ] Synthesis Path-Downstream   1~6

  • 3
  • [ 6638-05-7 ]
  • [ 530-55-2 ]
YieldReaction ConditionsOperation in experiment
With Galerina sp. HC1 laccase; oxygen; In aq. acetate buffer; at 22℃;pH 5.0;Enzymatic reaction; General procedure: For the oxidation reactions 5mM of a model compound was allowed to react with 0.4U/mL laccase in 20mM sodium acetate buffer pH 5, at room temperature (?22°C) with mixing on rocking table (Mixer 440, Swelab Instrument AB, Sweden). The reaction was stopped by adding sodium azide to the final concentration of 40muM. The coupling of equimolar amount of PABA (5mM) to the compounds was also investigated under similar conditions.
  • 4
  • [ 6638-05-7 ]
  • [ 7732-18-5 ]
  • oxygen [ No CAS ]
  • enzyme-substance from mushrooms [ No CAS ]
  • [ 530-56-3 ]
  • [ 530-55-2 ]
  • [ 15640-40-1 ]
  • [ 134-96-3 ]
  • 5
  • [ 634-36-6 ]
  • [ 530-55-2 ]
  • [ 19676-64-3 ]
YieldReaction ConditionsOperation in experiment
With potassium peroxymonosulfate; In [D3]acetonitrile; water-d2; at 20℃; for 5h; General procedure: To an NMR tube, 8.4 mg (50 µmoles) of 1 and 2.2 mg (30 µmoles) of tBuOH (used as an internal standard) in a 750 µL solution of 10% (v/v) d3-ACN in D2O were added. A 1H-NMR spectrum was recorded as a zero point (time = 0). A stock solution of 400 mM Oxone in 10% (v/v) d3-ACN in D2O was prepared and a 250 µL aliquot of the Oxone solution was added to the NMR tube to initiate the reaction. The reaction was followed by 1H-NMR spectroscopy over the course of 5 hrs at room temperature. The yields reported were based on the integration of aromatic peaks against the internal standard. This procedure was repeated for each of the different mol equivalents of Oxone, for the different cosolvents, and substrates.
  • 6
  • [ 634-36-6 ]
  • [ 530-55-2 ]
  • [ 3117-02-0 ]
  • [ 19676-64-3 ]
YieldReaction ConditionsOperation in experiment
With potassium peroxymonosulfate; In [D3]acetonitrile; water-d2; tert-butyl alcohol; at 20℃; for 5h;Schlenk technique; Inert atmosphere; To an NMR tube, 8.4 mg (50 µmoles) of 1 and 2.2 mg (30 µmoles) of tBuOH (used as an internal standard) in a 750 µL solution of 10% (v/v) d3-ACN in D2O were added. A 1H-NMR spectrum was recorded as a zero point (time = 0). A stock solution of 400 mM Oxone in 10% (v/v) d3-ACN in D2O was prepared and a 250 µL aliquot of the Oxone solution was added to the NMR tube to initiate the reaction. The reaction was followed by 1H-NMR spectroscopy over the course of 5 hrs at room temperature. The yields reported were based on the integration of aromatic peaks against the internal standard. This procedure was repeated for each of the different mol equivalents of Oxone, for the different cosolvents, and substrates.
 

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