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Chemical Structure| 19975-56-5 Chemical Structure| 19975-56-5
Chemical Structure| 19975-56-5

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Product Details of 2-(Methylthio)-2-thiazoline

CAS No. :19975-56-5
Formula : C4H7NS2
M.W : 133.24
SMILES Code : CSC1=NCCS1
MDL No. :MFCD00005312
InChI Key :QFGRBBWYHIYNIB-UHFFFAOYSA-N
Pubchem ID :88324

Safety of 2-(Methylthio)-2-thiazoline

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H315-H318-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P310-P332+P313-P362-P403+P233-P405-P501
Class:9
UN#:3334
Packing Group:

Application In Synthesis of 2-(Methylthio)-2-thiazoline

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 19975-56-5 ]

[ 19975-56-5 ] Synthesis Path-Downstream   1~3

  • 2
  • [ 19975-56-5 ]
  • [ 7149-18-0 ]
  • 2,3,7,8-tetrahydro-5H,6H-cyclopenta[1,2-d]thiazolo[3,2-a]pyrimidin-5-one [ No CAS ]
  • 3
  • [ 19975-56-5 ]
  • [ 129946-63-0 ]
  • 1,3-thiazolin-2-one(2,5-difluoro-4-cyanophenyl) hydrazone [ No CAS ]
YieldReaction ConditionsOperation in experiment
With trifluoroacetic acid; In methanol; ethyl acetate; Reference Example 15 1,3-Thiazolin-2-one(2,5-difluoro-4-cyanophenyl) hydrazone (Compound No. 3-4) 2-Methylthio-2-thiazoline (1.0g, 7.52mmol), and <strong>[129946-63-0]2,5-difluoro-4-cyanophenylhydrazine</strong> (1.27g, 7.51mmol) were dissolved in methanol (20ml), and to the resulting mixture, trifluoroacetic acid (four drops) was added at room temperature, and then the resultant was stirred at 55 ØC for 48 hours. After cooling, the reaction mixture was evaporated, and the obtained residue was dissolved in ethyl acetate, washed with sodium bicarbonate solution and dried, and then the solvent was removed. The obtained residue was purified by silicagel column chromatography (chloroform:acetone=25:1) to give 1,3-thiazolin-2-one(2,5-difluoro-4-cyanophenyl) hydrazone(0.9g). 1H-NMR(CDCl3) delta:3.33(2H,t,J=6.6Hz), 3.70(2H, t, J=6.6Hz), 6.10(1H,br s), 6.60-6.78(1H,m), 7.09-7.17(1H, m).
 

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