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Chemical Structure| 96424-68-9 Chemical Structure| 96424-68-9
Chemical Structure| 96424-68-9

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Product Details of 2-Bromo-3-chloropyridine

CAS No. :96424-68-9
Formula : C5H3BrClN
M.W : 192.44
SMILES Code : BrC1=NC=CC=C1Cl
MDL No. :MFCD04039344
InChI Key :GOHBBINNYAWQGO-UHFFFAOYSA-N
Pubchem ID :7016326

Safety of 2-Bromo-3-chloropyridine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302+H312+H332-H315-H319
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of 2-Bromo-3-chloropyridine

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 96424-68-9 ]

[ 96424-68-9 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 96424-68-9 ]
  • [ 1072951-54-2 ]
  • 2',3,6'-trichloro-2,4'-bipyridine [ No CAS ]
YieldReaction ConditionsOperation in experiment
74% With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; In 1,2-dimethoxyethane; water; at 90℃; for 2h;Inert atmosphere; Example 29.N-(3-chloro-6?-(S-( i-methyl-i H-pyrazol-4-yl)- 1 H-benzo[d}imidazol- l-yl)-[2,4?- bipyridinj-2?-yl)cyclopropanesulfonamidea) 2?,3,6?-Trichloro-2,4?-bipyridine A solution of <strong>[1072951-54-2](2,6-dichloropyridin-4-yl)boronic acid</strong> (0.76 g, 4 mmol) in 1,2- dimethoxyethane (15 ml) was degassed by N2 bubbling for 5 mm. 2-Bromo-3-chloro- pyridine (0.7 g, 3.63 mmol, 1.2 eq) was added and the mixture was degassed for another 5 mm. Pd(dppf)C12 (0.3 g, 0.36 mmol, 0.1 eq) and aqueous sodium carbonate (1.15 g,10.9 mmol, 3 eq) were added sequentially using the procedure of Intermediate Example1 and then heated at 90 C for 2 h. The reaction mixture was then quenched and extracted as in Intermediate Example 1. The solvent was distilled off to afford the crude residue which was purified by column chromatography (60-120 silica gel, 10 % ethyl acetate in hexane) to afford the title product in 74 % yield (0.7 g). ?H NMR (300 MHz,CDC13): oe 8.63 (dd, 1H),7.86 (m, III), 7.68 (s, 2H), 7.37 (dd, 1H).
  • 2
  • [ 96424-68-9 ]
  • [ 15016-42-9 ]
  • 3-chloro-2-(2-vinylphenyl)pyridine [ No CAS ]
  • 3
  • [ 96424-68-9 ]
  • [ 15016-42-9 ]
  • 1-chloro-7-methyl-6H-pyrido[2,1-a]isoquinolin-6-one [ No CAS ]
 

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