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Chemical Structure| 20050-82-2 Chemical Structure| 20050-82-2

Structure of 20050-82-2

Chemical Structure| 20050-82-2

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Product Details of [ 20050-82-2 ]

CAS No. :20050-82-2
Formula : C15H9ClO3
M.W : 272.68
SMILES Code : O=C1C(C2=CC=C(Cl)C=C2)=CC3=C(O1)C=C(O)C=C3
MDL No. :MFCD02093150

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Application In Synthesis of [ 20050-82-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 20050-82-2 ]

[ 20050-82-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 50-00-0 ]
  • [ 20050-82-2 ]
  • [ 494-52-0 ]
  • 7-hydroxy-8-[(2S)-2-pyridin-3-ylpiperidin-1-yl]methyl}-3-(4-chlorophenyl)-2H-chromen-2-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
86% With dmap; at 78℃; General procedure: The appropriate 7-hydroxycoumarin 1a-h (2 mmol) in refluxing anhydrous EtOH (25-30 mL) was treated with anabasine (2.5 mmol), paraformaldehyde (90 mg,3 mmol), and DMAP (2-5 mg), and refluxed for 20-30 h. The end of the reaction was determined by TLC. The mixture wascooled and diluted with hexane. The resulting precipitate was filtered off, dried, and crystallized from i-PrOH-hexane orpurified by column chromatography with elution by EtOAc.
 

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