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Chemical Structure| 202192-77-6 Chemical Structure| 202192-77-6

Structure of 202192-77-6

Chemical Structure| 202192-77-6

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Product Details of [ 202192-77-6 ]

CAS No. :202192-77-6
Formula : C17H12N2O4
M.W : 308.29
SMILES Code : O=C1NC2=C(C=C([N+]([O-])=O)C=C2)C(C3=CC=CC=C3)=C1C(C)=O

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Application In Synthesis of [ 202192-77-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 202192-77-6 ]

[ 202192-77-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3314-30-5 ]
  • [ 202192-77-6 ]
  • 3-(3-1H-benzoimidazol-2-ylacryloyl)-6-nitro-4-phenyl-1H-quinolin-2-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
26% With sodium hydroxide; In ethanol; at 20℃; Step 2 The mixture of NaOH (15.6 mg, 0.390 mmol), 3-acetyl-6-nitro-4-phenyl-1H-quinolin-2-one (100 mg, 0.325 mmol), <strong>[3314-30-5]1H-benzoimidazole-2-carbaldehyde</strong> (52.1 mg, 0.357 mmol) in ethanol (1 mL) was stirred at room temperature overnight. The reaction was diluted with DCM (10 mL) and washed with water (10 mL). The organic layer was evaporated to dryness and the residue was purified by pre-HPLC to afford 3-(3-1H-benzoimidazol-2-yl-acryloyl)-6-nitro-4-phenyl-1H-quinolin-2-one (36 mg, yield: 26percent) as yellow solid. 1HNMIt (400 MHz, DMSO-d6): delta=12.88 (s, 1H), 8.45 (dd, J=9.2, 2.4 Hz, 1H), 7.93 (d, J=2.4 Hz, 1H), 7.64 (m, 2H), 7.53-7.49 (m, 5H), 7.39-7.37 (m, 3H), 7.27-7.22 (m, 2H) , 7.06 (d, J=16.4 Hz, 1H). MS: m/z 437.1 (M+H+).
 

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