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Chemical Structure| 20599-01-3 Chemical Structure| 20599-01-3

Structure of 20599-01-3

Chemical Structure| 20599-01-3

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Product Details of [ 20599-01-3 ]

CAS No. :20599-01-3
Formula : C5H8Br2O2
M.W : 259.92
SMILES Code : BrCC1(CBr)OCCO1
MDL No. :MFCD15526789

Safety of [ 20599-01-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P280-P305+P351+P338-P310
Class:8
UN#:1759
Packing Group:

Application In Synthesis of [ 20599-01-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 20599-01-3 ]

[ 20599-01-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 20599-01-3 ]
  • [ 1520-70-3 ]
  • 1-(ethylsulfonyl)azetidin-3-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
94.1% With sodium carbonate; In 1,4-dioxane; at 65℃; for 16h; To 2 L reaction flask add 500g1, 4 - dioxane, 39.0 g (0.15 muM) compound 5, 31.8 g (0.3 muM) sodium carbonate and 18.0 g (0.17 muM) ethyl sulfonamide, system temperature to 65 °C, thermal insulation reaction 16 h, central control, raw material compound 5 basic reaction is complete. Stopping the reaction, system lower the temperature to the room temperature, is added to the system 500 g water and 500 g ethyl acetate, stirring, layered, the water layer 300 gX2 ethyl acetate extraction, the combined organic layer, the organic layer using 500 g water washing. Then the organic layer into the 2 L clean reaction bottle, room temperature stirring next adds by drops 30.4 g of concentrated hydrochloric acid. Then completing, stirring 1 h stratified, the organic layer using 500 g dry after washing, filtering, the filtrate is concentrated to half 300 g normal heptane, system cooling to 0 - 10 °C, thermal insulation beating 2 h the filter mass after drying to the compounders 6 about 23.0 g, yield: 94.1percent, HPLC ? 98.0percent.
 

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