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Chemical Structure| 208652-71-5 Chemical Structure| 208652-71-5

Structure of 208652-71-5

Chemical Structure| 208652-71-5

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Product Details of [ 208652-71-5 ]

CAS No. :208652-71-5
Formula : C16H16O4
M.W : 272.30
SMILES Code : O=C(C1=CC=C(C2=CC=C(OC)C=C2OC)C=C1)OC
MDL No. :MFCD27578745

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Application In Synthesis of [ 208652-71-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 208652-71-5 ]

[ 208652-71-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 619-42-1 ]
  • [ 133730-34-4 ]
  • [ 208652-71-5 ]
YieldReaction ConditionsOperation in experiment
With tetrabutylammomium bromide; potassium carbonate;palladium diacetate; In water; at 80℃; for 0.666667h; To a 100 mL flask, methyl 4-bromobenzoate (1.42 g), <strong>[133730-34-4]2,4-dimethoxybenzeneboronic acid</strong> (1.3 g), Pd (OAc)2 (100 mg), K2CO3 (1.9 g) and tetrabutylammonium bromide (3.54 g) were added. The flask was flushed with N2 and sealed with a rubber septum. Water (50 mL) was added with a syringe, and the resulting suspension was stirred and deoxygenated with N2 at room temperature. The mixture was stirred and heated for 40 min. at 80 C. under N2, cooled to room temperature, and acidified to pH 1 with concentrated HCl. The precipitate (Pd) was filtered off and washed with EtOAc. The filtrate was extracted with EtOAc, washed with saturated brine, dried over anhydrous Na2SO4 and concentrated to give crude product 23.
 

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