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Chemical Structure| 2131-64-8 Chemical Structure| 2131-64-8

Structure of 2131-64-8

Chemical Structure| 2131-64-8

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Product Details of [ 2131-64-8 ]

CAS No. :2131-64-8
Formula : C9H10N2S
M.W : 178.25
SMILES Code : CN(C1=CC=C(N=C=S)C=C1)C
MDL No. :MFCD00041093

Safety of [ 2131-64-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H312-H314-H315-H319-H332-H335
Precautionary Statements:P233-P260-P261-P264-P270-P271-P280-P301+P312-P301+P330+P331-P302+P352-P303+P361+P353-P304-P304+P340-P305+P351+P338-P310-P312-P321-P322-P330-P332+P313-P337+P313-P340-P362-P363-P403-P403+P233-P405-P501
Class:6.1(8)
UN#:2928
Packing Group:

Application In Synthesis of [ 2131-64-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2131-64-8 ]

[ 2131-64-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 120-35-4 ]
  • [ 2131-64-8 ]
  • 3-[3-(4-Dimethylaminophenyl)-thioureido]-4-methoxy-N-phenyl-benzamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
In ethyl acetate; Example 93 3- [3-(4-Dimethylaminophenyl)-thioureido]-4-methoxy-N-phenyl-benzamide A mixture of 3-amino-4-methoxy-N-phenyl-benzamide (0.975 g, 4.01 mmol), 4-(dimethylamino)phenyl isothiocyanate (0.716 g, 4.00 mmol), and ethyl acetate (20 mL) was allowed to stand at room temperature. After 5 days, the mixture was concentrated to two-thirds volume by rotary evaporator, allowed to stand overnight, then heated to 80 degrees for 4 hours. The precipitate was collected by filtration and the mother liquor heated to 80 degrees for another 3 hours. More precipitate was collected by filtration and the mother liquor again heated to 80 degrees and after 7 hours allowed to cool to room temperature overnight. The remaining liquor was concentrated to dryness and the residue triturated in hexanes and the solid filtered off and washed with ethyl acetate. Combination of all the lots gave the product (0.905 g); m.p. 179-180 C. Calculated for C23H24N4O2S.0.1 M EtOAc: C, 65.46; H, 5.82; N, 13.05. Found: C, 65.24; H, 5.70; N, 12.86.
 

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