Home Cart Sign in  
Chemical Structure| 21474-92-0 Chemical Structure| 21474-92-0

Structure of 21474-92-0

Chemical Structure| 21474-92-0

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 21474-92-0 ]

CAS No. :21474-92-0
Formula : C8H14O3
M.W : 158.20
SMILES Code : CC(C(C(=O)OCC)C=O)C
MDL No. :MFCD22548740

Safety of [ 21474-92-0 ]

Application In Synthesis of [ 21474-92-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 21474-92-0 ]

[ 21474-92-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 21474-92-0 ]
  • [ 456-14-4 ]
  • 2-(4-fluorophenyl)-5-isopropylpyrimidin-4-ol [ No CAS ]
YieldReaction ConditionsOperation in experiment
1 g With sodium hydrogencarbonate; In ethanol; at 85℃; for 16h; To the solution of <strong>[456-14-4]4-fluorobenzimidamide hydrochloride</strong> (1.0 g, 5.7 mmol, 1.0 eq.) and ethyl 2-formyl-3-methylbutanoate (1.17 g, 7.48 mmol, 1.3 eq.) in ethanol (20 ml) was added NaHCO3 (1.44 g, 17.06 mmol, 3.0 eq). Reaction mass was refluxed at 85 C for 16 hours. The progress of reaction was monitored by TLC and LCMS. Upon completion, the ethanol was removed under reduced pressure to get crude product. Crude product was triturated with n-pentane to give 1.0 g of 2-(4-fluorophenyl)-5-isopropylpyrimidin-4-ol. LCMS (M+1): 234.1 1H-NMR: (400 MHz, DMSO-d6): delta 8.08 - 8.21 (m, 2H), 7.89 (s, 1H), 7.34 (t, J = 8.77 Hz, 2H), 2.84-2.94 (m, 1H), 1.18 (d, J = 7.02 Hz, 6H).
 

Historical Records