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[ CAS No. 215162-34-8 ] {[proInfo.proName]}

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Chemical Structure| 215162-34-8
Chemical Structure| 215162-34-8
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Product Details of [ 215162-34-8 ]

CAS No. :215162-34-8 MDL No. :MFCD17012727
Formula : C12H12O9 Boiling Point : -
Linear Structure Formula :- InChI Key :OMPLWOKOQNOVCD-UHFFFAOYSA-N
M.W : 300.22 Pubchem ID :10828045
Synonyms :

Safety of [ 215162-34-8 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501 UN#:
Hazard Statements:H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 215162-34-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 215162-34-8 ]

[ 215162-34-8 ] Synthesis Path-Downstream   1~16

  • 1
  • [ CAS Unavailable ]
  • [ 215162-34-8 ]
  • [ 215161-32-3 ]
YieldReaction ConditionsOperation in experiment
89% With N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate In chloroform; N,N-dimethyl-formamide at 25℃; for 16h;
  • 2
  • [ 314241-45-7 ]
  • [ 215162-34-8 ]
YieldReaction ConditionsOperation in experiment
95% With sodium hydroxide at 80℃; for 12h;
  • 3
  • [ 478812-59-8 ]
  • [ 215162-34-8 ]
YieldReaction ConditionsOperation in experiment
99% With sodium hydroxide In water for 24h; Heating;
92% With Dowex 50 W-X8; water for 8h; Heating;
  • 4
  • [ 192803-37-5 ]
  • [ 215162-34-8 ]
  • [ 616873-79-1 ]
YieldReaction ConditionsOperation in experiment
63% With dmap; dacarbazine In dichloromethane
63% With dmap; diisopropylcyanamide In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃;
  • 5
  • [ 108-73-6 ]
  • [ 79-11-8 ]
  • [ 215162-34-8 ]
YieldReaction ConditionsOperation in experiment
89% With sodium hydroxide at 110℃; 1,3,5-Trihydroxybenzene (3.78 g, 0.013 mol), chloroacetic acid (3.4 g, 0.015 mol) and PEG-200 (0.6 g, 0.003 mol) was successively slowly added to 20 mL water containing NaOH (2 g, 0.05 mol) in ice bath. The solution was heated to 110 oC for 5-6 hours, and its pH value was detected during the reaction to keep the reaction system basic. After cooling and filtering, the filtrate was collected and its pH was slowly adjusted to 1 by HCl solution, and solid was precipitated. After filtering the solution and recrystallizing the solid, pure compound 7 was obtained in 89% yield. 2,2',2''-(benzene-1,3,5-triyltris(oxy))triacetic acid (compound 7): 1H NMR (400 MHz, DMSO) δ 6.06 (s, 2H), 4.54 (s, 3H); 13C NMR (100 MHz, DMSO) δ 170.20, 159.57, 94.26, 65.13.
79% With sodium hydroxide In water at 95 - 100℃; for 0.166667h; Microwave irradiation; Sonication; Green chemistry; 3.2.3. MW-US Method General procedure: In a 50 mL flask, 1mmol of phenol (1-15), the appropriate amount of chloroacetic acid (16) andsodium hydroxide (potassium carbonate for nipagins) and 5 mL of water were mixed.Number of moles of chloroacetic acid (16) and NaOH (K2CO3): 1.2 mmol (0.11 g) of 16 and 2.3 mmol of base for monophenols (1-9) 2.2 mmol (0.21 g) of 16 and 3.3 mmol of base for diphenols (10-12) 3.2 mmol (0.30 g) of 16 and 4.3 mmol of base for triphenols (13-15)A flask with carefully mixed reagents was placed in a MW-US reactor and the contents reactedunder SMUI conditions characterized by the following parameters: MW = 200 W, US = 800 Wat 95-100° C for 10 min. After the process was complete, concentrated hydrochloric acid wasadded to the reaction mixture until an acidic pH~3 was obtained, to isolate the free products. Theseparated precipitate was filtered off. The main product was purified by crystallization or columnchromatography using a mixture of chloroform and methanol (9:1 or 5:1) as an eluent.
55% Stage #1: chloroacetic acid With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1h; Stage #2: 3,5-dihydroxyphenol With potassium carbonate In N,N-dimethyl-formamide at 74 - 78℃; for 12h; Further stages.;
  • 6
  • [ 13121-70-5 ]
  • [ 215162-34-8 ]
  • [ 1962942-13-7 ]
YieldReaction ConditionsOperation in experiment
39.8% In methanol for 22h; Inert atmosphere; Reflux; 4 Example 4: Preparation of tricyclohexyltin 1,3,5-benzentrioxyacetate: To a 150mL three-necked flask under nitrogen protection was added 1.500g (5.0mmol) 1,3,5-benzenetrioxyacetate, 6.352g (16.5mmol) tricyclohexylstannyl hydroxide, 80mL of anhydrous methanol. It was stirred at reflux for 22h. After completion of the reaction, cooled to room temperature, filtered, and the pressure 0.004MPa, a temperature of 30 under the conditions, and the filtrate was evaporated to dryness with a rotary evaporator to give tricyclohexyltin trimesic oxygen acetate crude products, with dichloromethane - methanol mixed solvent recrystallized from methylene chloride and methanol wherein the volume ratio of 1: 4, at 15 ~ 35 conditions, control crystallization solvent evaporation to give a white solid that is tricyclohexyltin the present invention trimesic oxygen acetate. Yield: 39.8%.
  • 7
  • [ CAS Unavailable ]
  • [ CAS Unavailable ]
  • [ CAS Unavailable ]
  • [ 7732-18-5 ]
  • [ 215162-34-8 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
29.15% With hydrogenchloride at 20℃; for 4h; Reflux; Cs8NaH[(SeMo6O21)C6H3O3(CH2CO2)3]2.10H2O(1): TCMB(0.030 g, 0.10 mmol) was dissolved in 9 mL water, then under intensestirring Na2MoO42H2O (0.140 g, 0.60 mmol), SeO2 (0.011 g,0.10 mmol) and CsCl (0.034 g, 0.20 mmol) were added. The pH value ofthe solution was adjusted to 3.9 using 1 mol L1 HCl solution, then themixture was stirred for 2 h under ambient conditions. After another 2 h ofreflux, the mixture was cooled down to room temperature and filtered toa 25 mL beaker. The colorless columnar crystals were acquired after oneweek of standing. Yield: 29.15% (0.056 g) for 1 based onNa2MoO42H2O. Anal. Calcd (%) for 1: Mo 29.97, C 7.50, H 1.02, Found:Mo 31.26, C 7.44, H 1.15. IR (KBr pellet): 3402 (s), 1591 (s), 1459 (m),1430 (m), 1358 (m), 1172 (m), 1151 (m), 1088 (w), 907 (s), 783 (s), 749(s), 667 (s).
  • 8
  • [ CAS Unavailable ]
  • [ CAS Unavailable ]
  • [ 7732-18-5 ]
  • [ CAS Unavailable ]
  • [ 215162-34-8 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
39.96% With hydrogenchloride at 20℃; for 4h; Reflux; General procedure: TCMB(0.030 g, 0.10 mmol) was dissolved in 9 mL water, then under intensestirring Na2MoO42H2O (0.140 g, 0.60 mmol), SeO2 (0.011 g,0.10 mmol) and CsCl (0.034 g, 0.20 mmol) were added. The pH value ofthe solution was adjusted to 3.9 using 1 mol L1 HCl solution, then themixture was stirred for 2 h under ambient conditions. After another 2 h ofreflux, the mixture was cooled down to room temperature and filtered toa 25 mL beaker. The colorless columnar crystals were acquired after oneweek of standing. Yield: 29.15% (0.056 g) for 1 based onNa2MoO42H2O.
  • 9
  • [ 771-61-9 ]
  • [ 215162-34-8 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
82% With diisopropyl-carbodiimide In tetrahydrofuran at 20℃; Compound 7 (3.5 g, 0.012 mol), pentafluorophenol (2.6 g, 0.014 mol) and DIC (1.8 g, 0.014 mol) were added in flask with THF as solvent. The reaction was stirred overnight at room temperature and monitored by TLC. After the reaction was finished, the intermediate compound 8 was purified by column chromatography in 82% yield. tris(6,6,6,6,6-pentafluoro-6l8-hexa-1,3,5-triyn-1-yl) 2,2',2''-(benzene-1,3,5-triyltris(oxy))triacetate (compound 8): 1H NMR (400 MHz, CDCl3) δ 6.29 (s, 3H), 4.98 (s, 6H); 13C NMR (100 MHz, CDCl3) δ 164.66, 159.59, 142.39, 141.25, 139.88, 139.30, 136.79, 124.40, 96.25, 64.79; HRMS (ESI) m/z: [M+Na]+ calcd for C30H9F15O9 820.9899; found, 820.9898.
  • 10
  • [ 38634-05-8 ]
  • [ 7732-18-5 ]
  • [ 5970-45-6 ]
  • [ 215162-34-8 ]
  • [Zn2(1,3,5-tris(carboxylatomethoxy)benzene)(4-amino-3,5-bis(4-pyridyl)-1,2,4-triazole)(μ3-OH)]n·nH2O [ No CAS ]
  • 11
  • [ CAS Unavailable ]
  • [ 7732-18-5 ]
  • [ 215162-34-8 ]
  • [ 1135-32-6 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
In acetonitrile at 140℃; for 72h; Autoclave; Preparation of [Mn2(HL)2(bpe)(H2O)8]·5H2O}n (1) A mixture of H3L(15 mg, 0.05 mmol), MnCl2·4H2O (9.89,0.05 mmol mg), bpe (9.11 mg, 0.05 mmol), CH3CN(3 mL)and H2O(2 mL) was sealed in a 25-mL Teflon-lined autoclave,heated to 140 °C for 72 h and then cooled to roomtemperature. Yellow block crystals were obtained. Elementalanalysis calcd. (%) for C36H56Mn2N2O31:C 38.51, H 5.03,N 2.50. Found: C 38.49, H 5.09, N 2.55. IR (KBr, cm-1):1575(s), 1474(w), 1407(m), 1330(m), 1164(s), 1064(m),956(w), 808(w), 714(m), 560(w), 539(w).
  • 12
  • [ 7732-18-5 ]
  • [ CAS Unavailable ]
  • [ 215162-34-8 ]
  • [ 1135-32-6 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
In acetonitrile at 130℃; for 72h; Autoclave; Preparation of [Ni3(L)2(bpe)3(H2O)6]·3H2O}n (2) A mixture of H3L(15 mg, 0.05 mmol), Ni(Ac)3·4H2O(12.46 mg, 0.05 mmol), bpe (9.11 mg, 0.05 mmol), CH3CN(3 mL) and H2O(2 mL) was sealed in a 25-mL Teflonlinedautoclave, heated to 130 °C for 72 h and then cooledat 5 °C/h to room temperature. Green needle crystals wereobtained. Elemental analysis calcd. (%) for C60H66N6Ni3O27:C 48.72, H 4.50, N 5.68. Found: C 48.79, H 4.56, N 5.74. IR(KBr, cm-1): 1605(s), 1415(s), 1319(m), 1258(m), 1154(s),1077(m), 818(m), 705(w).
  • 13
  • [ CAS Unavailable ]
  • [ 7732-18-5 ]
  • [ 215162-34-8 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
30% With 1,2,3-Benzotriazole In ethanol at 100℃; for 72h; Sealed tube; Autoclave; 2.2. Preparation and characterization for [Co3 (TCMB)2(H2O)4]n•4nH2O(1)and [Zn3(TCMB)( μ3 -OH)3]n•0.5nH2O (2) For the complex 1 , through mixing the 60 mg and 0.20 mmol Co(NO3)2•6H2O, 15 mg and 0.05 mmol H3TCMB, and 12 mg and 0.1 mmol 1H-Benzotriazole with 4 mL of ethanol and 4 mL of wa- ter, we can gain a mixture, after that, sealed the mixture in the 15 mL reactor lined with Teflon and then heated it for three days at 100 °C. Thus, the pink crystals with sheet-shape were acquired with 30% yield on the basis of the H 3 TCMB. Anal. Calcd for the C 24 H 34 O 26 Co 3 : H, 3.74 and C, 31.49. Found: H, 3.85 and C, 31.22.
  • 14
  • [ CAS Unavailable ]
  • [ 7732-18-5 ]
  • [ 215162-34-8 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
44% With 1,2,3-Benzotriazole; tetrafluoroboric acid In ethanol at 100℃; for 72h; Sealed tube; Autoclave; For the complex 2 , via mixing the 48 mg and 0.20 mmol Zn(NO3)2•6H2O, 15 mg and 0.05 mmol H3 TCMB, and 12 mg and 0.1 mmol 1H-Benzotriazole, as well as 30 μL of the HBF4 (50% aq) with 4 mL of water and 4 mL of ethanol, we can gain a mix- ture, after that, sealed the mixture in the 15 mL reactor lined with Teflon and then heated it for three days at 100 °C. Thus, the color- less crystals with sheet-shape were acquired with 44% yield. Anal. Calcd for the C 12 H 13 O 12.5 Zn 3 : H, 2.39 and C, 26.31. Found: H, 2.45 and C, 27.23.
  • 15
  • [ 4916-57-8 ]
  • [ CAS Unavailable ]
  • [ 7732-18-5 ]
  • [ 215162-34-8 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
43% In methanol at 85℃; for 72h; Preparation and Characterization for[Cu4(TCMB)2(bpee)2(μ3-OH)2(H2O)2]n·12nH2O (1) and[Zn4(TCMB)2(bpee)2(μ3-OH)2(H2O)2]n·12nH2O (2 For the complex 1, through mixing 48 mg and 0.20 mmolCu(NO3)2·3H2O, 15 mg and 0.05 mmol H3TCMB, and18 mg and 0.10 mmol bpee with 4 mL of methanol, and 4mL of water in the 15 mL reactor lined with Teflon to producea mixture, and heated the obtainedmixture for 72 hours at 85 .Thus, we can acquire the blue crystals with rod-shape with43% yield. Anal. Calcd for the C48H68N4O34Cu4: N, 3.74;H,4.57 and C, 38.45. Found: N, 3.98; H, 4.61 and C, 38.45. ICPcalculated for Cu (wt%): C, 38.45; Found: 37.94.
  • 16
  • [ 4916-57-8 ]
  • [ CAS Unavailable ]
  • [ 7732-18-5 ]
  • [ 215162-34-8 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
43% In methanol at 85℃; for 72h; For the complex 2, through mixing 48 mg and 0.20 mmolZn(NO3)2·6H2O, 15 mg and 0.05mmol H3TCMB, 18mg and0.10 mmol bpee and 30 μL of HBF4 (50% aq) with 4 mL ofethanol, and 4 mL of water in the 15 mL reactor lined withTeflon to produce a mixture, and heated the obtained mixturefor three days at 85 . Thus, we can acquire the colorless crystalswith sheet-shape with 44% yield. Anal. Calcd for theC48H68N4O34Zn4: N, 3.72; H, 4.55 and C, 38.27. Found: N,3.87; H, 4.49 and C, 38.11. ICP calculated for Zn (wt%): C,17.36; Found: 17.68.
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