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Chemical Structure| 2153-28-8 Chemical Structure| 2153-28-8

Structure of 2153-28-8

Chemical Structure| 2153-28-8

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Product Details of [ 2153-28-8 ]

CAS No. :2153-28-8
Formula : C14H24O2
M.W : 224.34
SMILES Code : CCCC(OC(C1CC=C(C)CC1)(C)C)=O
MDL No. :MFCD00083087

Safety of [ 2153-28-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P264-P270-P301+P312-P330-P501

Application In Synthesis of [ 2153-28-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2153-28-8 ]

[ 2153-28-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 98-55-5 ]
  • [ 141-75-3 ]
  • [ 2153-28-8 ]
YieldReaction ConditionsOperation in experiment
20.91 g In tetrahydrofuran; for 3h; 17.6 g (0.2 mol) of butyric acid, 17.85 g (0.15 mol) of thionyl chloride was added, After mixing, the reaction was carried out at 60 C for 3 hours, 20 ml of a tetrahydrofuran solution containing 15.4 g (0 lmo 1) alpha-<strong>[98-55-5]terpineol</strong> was added, Continue to react for 3 hours, The reaction solution was adjusted to pH 6 to 7 with NaOH solution, and the organic layer was separated, The aqueous layer was extracted with ethyl acetate, the organic layers were combined, washed with saturated brine, Anhydrous Na2S04 dry overnight, evaporated solvent, column chromatography (silica gel 200 ~ 300 mesh), B petroleum ether and ethyl acetate (15: 1) as the eluent, the eluent was distilled off, The colorless liquid was 20.91 g, the rate was 92.4%.
  • 2
  • [ 106-31-0 ]
  • [ 98-55-5 ]
  • [ 2153-28-8 ]
YieldReaction ConditionsOperation in experiment
80.5% With p-toluenesulfonyl chloride; at 20℃; for 1.5h; General procedure: A mixture ofalpha-<strong>[98-55-5]terpineol</strong> (1, 2mmol), acid anhydride (3mL) and TsCl (0.2mmol) was stirred at room temperaturefor 1.5h, and then neutralized to pH7-8 with 10% NaOH aqueous solution, washed with water (2×10mL) and brine (10mL). The organic layer was separated and dried over anhydrous Na2SO4, then concentrated and purified by silica gel column chromatography (petroleum ether/ethyl acetate=1:5 v/v) to afford the desired products.
 

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