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[ CAS No. 23024-29-5 ] {[proInfo.proName]}

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Cat. No.: {[proInfo.prAm]}
Chemical Structure| 23024-29-5
Chemical Structure| 23024-29-5
Structure of 23024-29-5 * Storage: {[proInfo.prStorage]}
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Product Details of [ 23024-29-5 ]

CAS No. :23024-29-5 MDL No. :MFCD00216005
Formula : C18H24N2O8 Boiling Point : -
Linear Structure Formula :- InChI Key :XPKIVYVYXKPGBP-UHFFFAOYSA-N
M.W : 396.39 Pubchem ID :3430836
Synonyms :
Disuccinimidyl sebacate;DSSeb;DSSeb Crosslinker, DSSeb Cross linker, DSSeb Cross-linker;Sebacic acid bis N-succinimidyl ester
Chemical Name :Bis(2,5-dioxopyrrolidin-1-yl) decanedioate

Safety of [ 23024-29-5 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 23024-29-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 23024-29-5 ]

[ 23024-29-5 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 6066-82-6 ]
  • [ 111-20-6 ]
  • [ 23024-29-5 ]
YieldReaction ConditionsOperation in experiment
With dicyclohexyl-carbodiimide In tetrahydrofuran
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In acetone at 25℃; for 24h; Experimental General procedure: NHS-Cn was prepared as described by Chen et al. (2011) with a small modification; end-bit binary acid (15 mmol each; C2, C3, C4, C5, C6, C8, C10, C14) and NHS (40 mmol) were dissolved in acetone (25 mL), and then EDC (30 mmol) was added to the solution. The clear mixture was gently stirred at 25°C for 24 h. After the acetone was removed by rotary evaporation under reduced pressure, the residue was washed several times with deionised water and then dried under vacuum at 50°C. The crosslinker thus prepared was characterised by the 1H NMR and FT-IR spectra.
  • 2
  • [ 25528-46-5 ]
  • [ 23024-29-5 ]
  • Sebacoyl-Lys(Z)-OEt [ No CAS ]
YieldReaction ConditionsOperation in experiment
With toluene-4-sulfonic acid; triethylamine In chloroform Yield given;
  • 3
  • [ 23024-29-5 ]
  • 4-(6-Amino-hexylamino)-1-{(2R,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-5-methyl-1H-pyrimidin-2-one [ No CAS ]
  • 9-[6-(1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-5-methyl-2-oxo-1,2-dihydro-pyrimidin-4-ylamino)-hexylcarbamoyl]-nonanoic acid 2,5-dioxo-pyrrolidin-1-yl ester [ No CAS ]
  • 4
  • Eu(3+)*N2C4H2(C5H3NCH2N(CH2CO2)2)C5H3NCH2N(CH2CO2)CH(CO2)(CH2)4NH2(4-)*Na(1+)=(Eu(C28H29N7O8))Na [ No CAS ]
  • [ 121-44-8 ]
  • [ 23024-29-5 ]
  • Eu(3+)*N2C4H2(C5H3NCH2N(CH2CO2)2)C5H3NCH2N(CH2CO2)CH(CO2)C4H8NHCO(CH2)8CONHC26H37N6O10(4-)*(C2H5)3NH(1+)=EuC70H98N15O20 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With NaHCO3 In water; dimethyl sulfoxide mixt. of Eu complex and Et3N in DMSO added at room temp. every 30 min tosoln. of disuccinimidyl sebacate in DMSO with stirring; left at room te mp. for 45 min; mixed with soln. of peptide in aq. NaHCO3 (pH 8.7); stirred at room temp. overnight; purified by semi-preparative RP-HPLC; lyophilised; detd. by mass spectra;
  • 5
  • Eu(3+)*N2C4H2(C5H3NCH2N(CH2CO2)2)C5H3NCH2N(CH2CO2)CH(CO2)(CH2)4NH2(4-)*Na(1+)=(Eu(C28H29N7O8))Na [ No CAS ]
  • [ 23024-29-5 ]
  • Eu(3+)*N2C4H2(C5H3NCH2N(CH2CO2)2)C5H3NCH2N(CH2CO2)CH(CO2)(CH2)4NHCO(CH2)8CO2NC4H4O2(4-)*Na(1+)=(Eu(C42H48N8O13))Na [ No CAS ]
YieldReaction ConditionsOperation in experiment
With Et3N In dimethyl sulfoxide mixt. of Eu complex and Et3N in DMSO added at room temp. every 30 min tosoln. of disuccinimidyl sebacate in DMSO with stirring; left at room te mp. for 45 min; detd. by mass spectra;
  • 6
  • [ 23024-29-5 ]
  • [1-deamino,8-lysine]vasotocin [ No CAS ]
  • C96H146N24O26S4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
52% With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 6h;
  • 7
  • [ 1022150-12-4 ]
  • [ 23024-29-5 ]
  • 2,5-dioxopyrrolidin-1-yl (R)-10-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-10-oxodecanoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
30% In N,N-dimethyl-formamide at 20℃; for 1h;
30% In N,N-dimethyl-formamide at 20℃; for 1h;
  • 8
  • [ 23024-29-5 ]
  • C49H51ClN8O6 [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: N,N-dimethyl-formamide / 1 h / 20 °C 2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
Multi-step reaction with 2 steps 1: N,N-dimethyl-formamide / 1 h / 20 °C 2: trifluoroacetic acid / dichloromethane / 2 h / 0 - 20 °C
  • 9
  • [ 23024-29-5 ]
  • C54H59ClN8O7 [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: N,N-dimethyl-formamide / 1 h / 20 °C 2: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C 3: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide
Multi-step reaction with 3 steps 1: N,N-dimethyl-formamide / 1 h / 20 °C 2: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 - 20 °C 3: trifluoroacetic acid / dichloromethane / 2 h / 0 - 20 °C
  • 10
  • [ 23024-29-5 ]
  • C41H49N7O7 [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: N,N-dimethyl-formamide / 1 h / 20 °C 2: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C
Multi-step reaction with 2 steps 1: N,N-dimethyl-formamide / 1 h / 20 °C 2: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 - 20 °C
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