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Chemical Structure| 239072-80-1 Chemical Structure| 239072-80-1

Structure of 239072-80-1

Chemical Structure| 239072-80-1

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Product Details of [ 239072-80-1 ]

CAS No. :239072-80-1
Formula : C12H14ClN3O
M.W : 251.71
SMILES Code : N#CC1=CC=C(CN2C(CNCC2)=O)C=C1.[H]Cl
MDL No. :MFCD20441583

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Application In Synthesis of [ 239072-80-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 239072-80-1 ]

[ 239072-80-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 239072-80-1 ]
  • [ 102153-63-9 ]
  • [ 239072-81-2 ]
YieldReaction ConditionsOperation in experiment
With sodium carbonate; In water; ethyl acetate; Reference Example 6 4-(6-Chloronaphthalene-2-sulfonyl)-1-(4-cyanobenzyl)-2-piperazinone A mixture of 1-(4-cyanobenzyl)-2-piperazinone hydrochloride (201 mg), 6-chloronaphthalene-2-sulfonyl chloride (205 mg), sodium carbonate (254 mg), ethyl acetate (10 ml) and water (5 ml) was stirred at room temperature for 2 hours. The organic layer was separated, washed with saturated brine, dried (MgSO4) and concentrated. The residue was purified with silica gel column chromatography (hexane:ethyl acetate=1:2) to give pale pink crystals of the title compound (239 mg). 1H-NMR (CDCl3) δ: 3.37 (4H, s), 3.87 (2H, s), 4.59 (2H, s), 7.28 (2H, d, J=7.9 Hz), 7.57 (2H, d, J=7.9 Hz), 7.58-7.66 (1H, m), 7.78 (1H, dd, J=8.5, 1.9 Hz), 7.90-7.98 (3H, m), 8.35 (1H, d, J=1.4 Hz). IR (KBr): 2232, 1651, 1346, 1167, 698 cm-1.
 

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