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Chemical Structure| 24074-84-8 Chemical Structure| 24074-84-8

Structure of 24074-84-8

Chemical Structure| 24074-84-8

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Product Details of [ 24074-84-8 ]

CAS No. :24074-84-8
Formula : C5H9ClN6
M.W : 188.62
SMILES Code : N=C(N1N=CC=C1)NC(N)=N.[H]Cl
MDL No. :N/A

Safety of [ 24074-84-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 24074-84-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 24074-84-8 ]

[ 24074-84-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 29390-67-8 ]
  • [ 24074-84-8 ]
  • [ 1584978-73-3 ]
YieldReaction ConditionsOperation in experiment
16% With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20℃; for 72h; b-biGCD was prepared from the intermediate 6-monodeoxy-6-monoamino-b-cyclodextrin (b-ACD), which was first preparedfrom b-cyclodextrin (b-CD) through a series of reactions. To a solutionof b-ACD (1.134 g, 1.000 mmol) in dry dimethylformamide(DMF) was added diisopropylethylamine (DIEA) (2.5 mL,0.120 mmol) followed by L2 (0.230 g,1.220 mmol). The mixturewasstirred for 72 h at room temperature.36,37 At the end of the reaction,15 mL of ether was added, and the resulting sticky solid productwas collected, washed using ether, and dried in vacuo to yield0.235 g (19percent) of crude product. The crude product was purified bycolumn chromatography on Sephadex G-25 using deionized wateras eluent. 0.18 g (16percent) pale crystalline solid was precipitated fromacetone/ether.1H NMR (500 MHz, DMSO-d6, ppm) 7.93 (2H, d,C44H73N3O34N2H2), 2.00 (2H, s, C44H73N3O34N2H2), 6.57 (2H, s,C44H73N4O34NH2), 4.30e4.72 (20H, m, eOH), 4.88e4.82 (7H, m,eCH); 13C NMR dH (500 MHz, DMSO-d6, ppm) 162.7 (1C, s,C43H75N2O34CN3), 162.1 (1C, s, C43H75N2O34CN3), 101.9 (7C, s, eCH),59.8e77.9 (m, 34C, eCH2); MS (ESI, H2O, m/z) [MH] calcd 1218.3,found 1218.5. Anal. Calcd for (C44H75N5O34)(H2O)8: C (38.80), H(6.73), N (5.14). Found C (38.83), H (6.67), N (5.18)
 

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