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Chemical Structure| 2417-63-2 Chemical Structure| 2417-63-2

Structure of 2417-63-2

Chemical Structure| 2417-63-2

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Product Details of [ 2417-63-2 ]

CAS No. :2417-63-2
Formula : C11H15BrO
M.W : 243.14
SMILES Code : CCCCOC1=CC=CC=C1CBr
MDL No. :MFCD11103152

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Application In Synthesis of [ 2417-63-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2417-63-2 ]

[ 2417-63-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2417-63-2 ]
  • [ 5932-27-4 ]
  • [ 1253113-42-6 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In N,N-dimethyl-formamide; at 20℃; for 24h;Inert atmosphere; Intermediate 16: Ethyl 1 -U2-(putyloxy)phenyl1methyl'HH-pyrazole-3- carboxylate; To ethyl 1 H-pyrazole-3-carboxylate (1.74 g, 12.4 mmol, ChemCollect GmbH) and potassium carbonate (3.43 g, 24.8 mmol) was added 1-(bromomethyl)-2- (butyloxy)benzene (3.0 g, 12.3 mmol) as a solution in DMF, washing in with further DMF to give a total volume of 35 ml. The mixture was stirred under nitrogen at ambient temperature. After 24 h the reaction was concentrated in vacuo. The residue was partitioned between EtOAc and water (approximately 100 ml each). The layers were separated and the aqueous was extracted with further EtOAc (2 x 50 ml). The combined organic extracts were washed with brine, dried (MgSO4) and concentrated in vacuo to give a pale yellow oil, which partially solidified on standing. The material was loaded in dichloromethane and purified on silica (Si) 100 g using 0- 100percent ethyl acetate-cyclohexane. The appropriate fractions were combined and concentrated in vacuo to give the title compound (2.07 g); LCMS: (System 4) MH+ = 303, tRET = 3.27 min.
 

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