Home Cart 0 Sign in  
X

[ CAS No. 24262-66-6 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
3d Animation Molecule Structure of 24262-66-6
Chemical Structure| 24262-66-6
Chemical Structure| 24262-66-6
Structure of 24262-66-6 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 24262-66-6 ]

Related Doc. of [ 24262-66-6 ]

Alternatived Products of [ 24262-66-6 ]
Product Citations

Product Details of [ 24262-66-6 ]

CAS No. :24262-66-6 MDL No. :MFCD00017517
Formula : C10H10O4 Boiling Point : -
Linear Structure Formula :C6H4(C2H3O2)2 InChI Key :PGJQPLVEUVHSFQ-UHFFFAOYSA-N
M.W : 194.18 Pubchem ID :578495
Synonyms :

Safety of [ 24262-66-6 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 24262-66-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 24262-66-6 ]
  • Downstream synthetic route of [ 24262-66-6 ]

[ 24262-66-6 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 24262-66-6 ]
  • [ 16357-40-7 ]
YieldReaction ConditionsOperation in experiment
11.5 g at 140℃; for 5 h; Methyl 4-acetylbenzoate (1002-95) (14 g, 66 mmol, 1.0 equiv)After grinding into powder, aluminum trichloride (26.3 g, 198 mmol, 3.0 equivalents) was added.Stir at 140°C for 5 hoursAfter the reaction was completed, a dark brown coagulated solid was cooled to room temperature.Crushed with a spoon and added to 300 ml of an aqueous solution. The mixture was heated to reflux for 3 hours. The reaction solution was made into a clear solution, cooled to room temperature, and concentrated hydrochloric acid was added dropwise to pH 1. A large amount of white solid was precipitated and filtered.Drying gave white solid 3-acetyl-4-hydroxybenzoic acid (11.5 g, 96.8percent overall yield over two steps).
Reference: [1] Journal of Medicinal Chemistry, 2018, vol. 61, # 7, p. 3037 - 3058
[2] Archiv der Pharmazie (Weinheim, Germany), 1942, vol. 280, p. 76,82
[3] Patent: US4259340, 1981, A,
[4] Patent: WO2004/80979, 2004, A1, . Location in patent: Page 22, 35, 36
[5] Bulletin of the Korean Chemical Society, 2017, vol. 38, # 1, p. 70 - 77
[6] Patent: CN107383024, 2017, A, . Location in patent: Paragraph 0269
  • 2
  • [ 24262-66-6 ]
  • [ 57009-12-8 ]
Reference: [1] Archiv der Pharmazie (Weinheim, Germany), 1942, vol. 280, p. 76,82
Recommend Products
Same Skeleton Products
Historical Records