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Chemical Structure| 245450-04-8 Chemical Structure| 245450-04-8

Structure of 245450-04-8

Chemical Structure| 245450-04-8

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Product Details of [ 245450-04-8 ]

CAS No. :245450-04-8
Formula : C13H20N6O4
M.W : 324.34
SMILES Code : O=[N+](C1=C(N)N=CN=C1N2CCN(C(OC(C)(C)C)=O)CC2)[O-]
MDL No. :MFCD11040203

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Application In Synthesis of [ 245450-04-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 245450-04-8 ]

[ 245450-04-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4316-94-3 ]
  • [ 57260-71-6 ]
  • [ 245450-04-8 ]
YieldReaction ConditionsOperation in experiment
87% With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20℃; for 8.0h; Compound 1 (1.91 g, 11 mmol) and diisopropylethylamine (1.55 g, 12 mmol) were added to a solution of the compound compound mono-tert-butoxycarbonyl protected piperazine (1.86 g, 10 mmol) in dimethylformamide (10 mL) ), The reaction was carried out at room temperature for 8 hours. The solvent was removed under reduced pressure and the residue was subjected to flash column chromatography (dichloromethane: methanol = 50: 1) to give the title compound as a white solid. B: 4- (6-Amino-5-nitropyrimidine- 4-yl) piperazine-1-carbonate (2.82 g, yield 87%).
 

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