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Chemical Structure| 2467-02-9 Chemical Structure| 2467-02-9

Structure of 2467-02-9

Chemical Structure| 2467-02-9

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Product Details of [ 2467-02-9 ]

CAS No. :2467-02-9
Formula : C13H12O2
M.W : 200.23
SMILES Code : OC1=CC=CC=C1CC2=CC=CC=C2O
MDL No. :MFCD00002243
InChI Key :MQCPOLNSJCWPGT-UHFFFAOYSA-N
Pubchem ID :75575

Safety of [ 2467-02-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 2467-02-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2467-02-9 ]

[ 2467-02-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 13352-76-6 ]
  • [ 108-95-2 ]
  • [ 2467-02-9 ]
  • [ 2467-03-0 ]
  • [ 620-92-8 ]
YieldReaction ConditionsOperation in experiment
With phosphoric acid; In water; at 80℃; for 4.0h; To 250ml four-necked flask was added under mechanical stirring phenol (phenol and paraformaldehyde dimethyl ether molar ratio of 15:1), phosphoric acid (the molar ratio of phosphoric acid to paraformaldehyde dimethyl ether is 6.4: 1) and water (molar ratio of water and paraformaldehyde dimethyl etherRatio of 14: 1), the water bath was slowly heated to 80 C, and then 5 g of paraformaldehyde dimethyl ether was slowly added dropwise during the controlTemperature between 75 -85 C . Bi completed, maintaining the temperature at 80 C to continue the reaction 4h. Complete the reaction of raw materials, natural cooling to 45 C ,The reaction solution was poured into a separatory funnel, standing stratification, the lower phosphoric acid aqueous solution recovery applied. After the upper organic phase is neutralized by alkali,Concentrated under reduced pressure, the application of excess phenol recovery. The concentrate was diluted with ethyl acetate and washed successively with saturated aqueous ammonium chloride solutionWashed with water, dried over anhydrous sodium sulfate, suction filtered, the filtrate was concentrated to dry twice to obtain the crude product. Crude by high pressure liquid chromatographyMeasured, bisphenol F yield, selectivity and product distribution in Table 2.
  • 2
  • [ 13353-03-2 ]
  • [ 108-95-2 ]
  • [ 2467-02-9 ]
  • [ 2467-03-0 ]
  • [ 620-92-8 ]
YieldReaction ConditionsOperation in experiment
With phosphoric acid; In water; at 80℃; for 4.0h; To 250ml four-necked flask was added under mechanical stirring phenol (phenol and paraformaldehyde dimethyl ether molar ratio of 15:1), phosphoric acid (the molar ratio of phosphoric acid to paraformaldehyde dimethyl ether is 6.4: 1) and water (molar ratio of water and paraformaldehyde dimethyl etherRatio of 14: 1), the water bath was slowly heated to 80 C, and then 5 g of paraformaldehyde dimethyl ether was slowly added dropwise during the controlTemperature between 75 -85 C . Bi completed, maintaining the temperature at 80 C to continue the reaction 4h. Complete the reaction of raw materials, natural cooling to 45 C ,The reaction solution was poured into a separatory funnel, standing stratification, the lower phosphoric acid aqueous solution recovery applied. After the upper organic phase is neutralized by alkali,Concentrated under reduced pressure, the application of excess phenol recovery. The concentrate was diluted with ethyl acetate and washed successively with saturated aqueous ammonium chloride solutionWashed with water, dried over anhydrous sodium sulfate, suction filtered, the filtrate was concentrated to dry twice to obtain the crude product. Crude by high pressure liquid chromatographyMeasured, bisphenol F yield, selectivity and product distribution in Table 2.
 

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