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Chemical Structure| 24690-19-5 Chemical Structure| 24690-19-5

Structure of 24690-19-5

Chemical Structure| 24690-19-5

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Product Details of [ 24690-19-5 ]

CAS No. :24690-19-5
Formula : C7H9NO3S
M.W : 187.22
SMILES Code : CS(=O)(OC1=CC=C(N)C=C1)=O

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Application In Synthesis of [ 24690-19-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 24690-19-5 ]

[ 24690-19-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 24690-19-5 ]
  • [ 53554-29-3 ]
  • [ 1430097-79-2 ]
YieldReaction ConditionsOperation in experiment
31% In butan-1-ol;Reflux; Step-I: Preparation of ethyl 4-hydroxy-2-((4-((methylsulfonyl)oxy)phenyl)amino)pyrimidine-5-carboxyIate.A mixture of commercially available <strong>[53554-29-3]ethyl 4-hydroxy-2-(methylthio)pyrimidine-5-carboxylate</strong> (35 g, 0.16 mol), 4-aminophenyl methanesulfonate (36.7 g, 0.196 mol) in Mrbutanol (175 mL) was refluxed for 4-5 h. After completion of reaction the mixture was cooled to 25-30 C and EtOAc (200 mL) was added and stirred mixture for 1 h. The pptd compound was filtered and washed with cold EtOAc to get desired title product (18 g, 31%).
 

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