Home Cart 0 Sign in  

[ CAS No. 25016-09-5 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 25016-09-5
Chemical Structure| 25016-09-5
Structure of 25016-09-5 * Storage: {[proInfo.prStorage]}

Quality Control of [ 25016-09-5 ]

Related Doc. of [ 25016-09-5 ]

SDS
Alternatived Products of [ 25016-09-5 ]
Alternatived Products of [ 25016-09-5 ]

Product Details of [ 25016-09-5 ]

CAS No. :25016-09-5 MDL No. :MFCD02681907
Formula : C6H8N2O Boiling Point : 227.7°C at 760 mmHg
Linear Structure Formula :- InChI Key :-
M.W :124.14 g/mol Pubchem ID :2776362
Synonyms :

Safety of [ 25016-09-5 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 25016-09-5 ]

  • Upstream synthesis route of [ 25016-09-5 ]
  • Downstream synthetic route of [ 25016-09-5 ]

[ 25016-09-5 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 57012-20-1 ]
  • [ 25016-09-5 ]
YieldReaction ConditionsOperation in experiment
34% With dipyridinium dichromate In dichloromethane at 25℃; for 16 h; Step 2:
Preparation of 2,5-dimethyl-2H-pyrazole-3-carbaldehyde (15)
A mixture of compound 14 (3 grams, 23.8 mmol) and pyridinium dichromate (13.4 grams, 35.7 mmol) in dichloromethane (100 mL) was stirred at 25° C. under nitrogen atmosphere for 16 hours.
The reaction mixture was then filtered.
The filtrate was collected, dried over anhydrous Na2SO4 and concentrated under reduced pressure.
The crude thus obtained was passed through the silica gel to afford the desired compound 2,5-dimethyl-2H-pyrazole-3-carbaldehyde (15) 1 gram as a brown solid.
Yield: 34percent; 1H NMR (200 MHz, CDCl3): δ 9.8 (s, H), 6.6(s, H), 4.1 (s, 3H), 2.3 (s, 3H). Mass (CI method, i-butane): 125 (M+1, 100percent); IR: νmax (KBr, cm-1): 1688.
Reference: [1] Patent: US2006/128729, 2006, A1, . Location in patent: Page/Page column 98
[2] Patent: WO2005/9941, 2005, A1, . Location in patent: Page 45-46
[3] Patent: WO2009/101082, 2009, A1, . Location in patent: Page/Page column 71
  • 2
  • [ 10250-59-6 ]
  • [ 25016-09-5 ]
Reference: [1] Patent: WO2009/101082, 2009, A1,
Historical Records

Related Functional Groups of
[ 25016-09-5 ]

Aldehydes

Chemical Structure| 27258-33-9

[ 27258-33-9 ]

1-Methyl-1H-pyrazole-5-carbaldehyde

Similarity: 0.87

Chemical Structure| 864068-96-2

[ 864068-96-2 ]

1-Methyl-3-phenyl-1H-pyrazole-5-carbaldehyde

Similarity: 0.86

Chemical Structure| 100305-93-9

[ 100305-93-9 ]

1-Isopropyl-1H-pyrazole-5-carbaldehyde

Similarity: 0.81

Chemical Structure| 2644-93-1

[ 2644-93-1 ]

1,3,5-Trimethyl-1H-pyrazole-4-carbaldehyde

Similarity: 0.80

Chemical Structure| 132274-70-5

[ 132274-70-5 ]

1-Phenyl-1H-pyrazole-5-carbaldehyde

Similarity: 0.79

Related Parent Nucleus of
[ 25016-09-5 ]

Pyrazoles

Chemical Structure| 87375-38-0

[ 87375-38-0 ]

1-(1,3-Dimethyl-1H-pyrazol-5-yl)ethanone

Similarity: 0.90

Chemical Structure| 27258-33-9

[ 27258-33-9 ]

1-Methyl-1H-pyrazole-5-carbaldehyde

Similarity: 0.87

Chemical Structure| 864068-96-2

[ 864068-96-2 ]

1-Methyl-3-phenyl-1H-pyrazole-5-carbaldehyde

Similarity: 0.86

Chemical Structure| 136678-93-8

[ 136678-93-8 ]

1,3-Dimethyl-1H-pyrazole-5-carboxamide

Similarity: 0.86

Chemical Structure| 1072-91-9

[ 1072-91-9 ]

1,3,5-Trimethylpyrazole

Similarity: 0.85