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Chemical Structure| 25044-03-5 Chemical Structure| 25044-03-5

Structure of 25044-03-5

Chemical Structure| 25044-03-5

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Product Details of [ 25044-03-5 ]

CAS No. :25044-03-5
Formula : C6H10O2
M.W : 114.14
SMILES Code : CC(C)C(CC=O)=O
MDL No. :MFCD17234334

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Application In Synthesis of [ 25044-03-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 25044-03-5 ]

[ 25044-03-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 25044-03-5 ]
  • [ 108290-86-4 ]
  • ethyl 4-isopropylpyrrolo[1,2-a]pyrimidine-8-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
60 mg With acetic acid; In ethyl acetate; at 110℃; for 2h; [00436] To a mixture of ethyl 2-amino-lH-pyrrole-3-carboxylate (1.23 g, 8.0 mmol) in AcOH (10 mL) at 110 C was added the solution of 4-methyl-3-oxopentanal in EtOAc. The reaction mixture was stirred at 110 C for 2 h, then cooled to RT and concentrated in vacuo. The resulting residue was purified by silica gel column (EA:PE; 85: 15) to afford ethyl 4- isopropylpyrrolo[l,2-a]pyrimidine-8-carboxylate (60 mg, 3.0%). XH NMR (400 MHz, CDC13): delta 8.47 (d, J= 4.0 Hz, 1H), 7.49 (d, J= 3.2 Hz, 1H), 7.21 (d, J= 3.2 Hz, 1H), 6.65 (d, J= 4.4 Hz, 1H), 4.43 (q, J= 7.2 Hz, 2H), 3.29-3.26 (m, 1H), 1.44-4.37 (m, 9H).
 

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