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Chemical Structure| 2555-37-5 Chemical Structure| 2555-37-5

Structure of 2555-37-5

Chemical Structure| 2555-37-5

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Product Details of [ 2555-37-5 ]

CAS No. :2555-37-5
Formula : C11H8O4
M.W : 204.18
SMILES Code : O=C1C(C(C)=O)=C(O)C2=C(O1)C=CC=C2
MDL No. :MFCD00138133
InChI Key :UTZHUXAPJIBIBQ-UHFFFAOYSA-N
Pubchem ID :54677403

Safety of [ 2555-37-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H332
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501

Application In Synthesis of [ 2555-37-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2555-37-5 ]

[ 2555-37-5 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 2555-37-5 ]
  • [ 6971-45-5 ]
  • [ 110570-16-6 ]
  • 2
  • [ 83279-39-4 ]
  • [ 2555-37-5 ]
  • 4-hydroxy-3-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-1-oxo-2-propenyl]-2H-1-benzopyran-2-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
With piperidine; In chloroform; for 2.5h;Heating / reflux; Example 6; Synthesis of the present intermediate (II-2c) [Compound No. (1c-6)]; A mixture of 2.25 g of 3-acetyl-4-hydroxy-2H-1-benzopyran-2-one, 2.25 g of <strong>[83279-39-4]3-chloro-4-(trifluoromethoxy)benzaldehyde</strong>, 20 ml of chloroform and 0.7 ml of piperidine was heated under refluxing for 2 hours and 30 minutes. After cooled to room temperature, the reaction mixture was concentrated under reduced pressure, and the residue was subjected to column chromatography. Resulting crystals were washed with 40 ml of t-butyl methyl ether to obtain 1.49 g of 4-hydroxy-3-[3-[3-chloro-4-(trifluoromethoxy)phenyl]-1-oxo-2-propenyl]-2H-1-benzopyran-2-one [Compound No. (1c-6)] was obtained as a yellow crystal.
  • 3
  • [ 2555-37-5 ]
  • [ 33906-30-8 ]
  • 2-(3-methyl-4-oxochromeno[4,3-c]pyrazol-1(4H)-yl)benzoic acid [ No CAS ]
  • 4
  • [ 2555-37-5 ]
  • [ 33906-30-8 ]
  • 2-(2-(1-(2-oxo-2H-chromen-3-yl)ethylidene)hydrazinyl)benzoic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
92% A mixture of the suitable <strong>[33906-30-8]2-hydrazinobenzoic acid hydrochloride</strong> [30] (2.58mmol) and 78 triethylamine (2.58mmol) in 32 EtOH (30mL) was stirred at reflux for 5-10min, then the 30 3-acetyl-4-hydroxy-2H-chromen-2-one 5 (1.29mmol) was added and the mixture was heated for an additional 30min. After cooling at room temperature, the 79 solid was collected, washed with water (about 10-20mL) and recrystallized. Yield 92%; mp 245-246C (EtOH); 1H NMR (DMSOd6): delta 2.69 (s, 3H, CH3), 6.97 (t, 1H, ar, J=7.6Hz), 7.02 (d, 1H, ar, J=8.5Hz), 7.32-7.37 (m, 2H, ar), 7.57 (t, 1H, ar, J=8.5Hz), 7.66 (t, 1H, J=7.8Hz), 7.96 (d, 1H, ar, J=7.8Hz), 8.00 (d, 1H, ar, J=7.6Hz), 10.28 (s, 1H, NH), 13.37 (br s, 1H, OH) Anal. C18H14N2O5 (C, H, N).
  • 5
  • [ 2555-37-5 ]
  • [ 36997-31-6 ]
  • C42H30N6O12 [ No CAS ]
YieldReaction ConditionsOperation in experiment
56% In methanol; for 24.0h;Reflux; General procedure: These ligands were synthesized by a general procedure. Synthesis of H6L1 (I) is presented here. A methanolic (20 mL) suspension of the <strong>[36997-31-6]benzene-1,3,5-tricarbohydrazide</strong> (H3bthz) (0.252 g, 1 mmol) was added to 3-acetyl-2-hydroxy-6-methyl-4H-pyran-4-one (2.12 g, 3 mmol) dissolved in MeOH (70 mL) and the reaction mixture was heated at reflux inan oil bath along with slow magnetic stirring. The trihydrazide slowly went into solution in ca. 3 h. After ca. 24 h of reflux, a clear solution was cooled to room temperature where a pale yellow solid slowly precipitated. The solid was filtered, washed with methanol and dried under vacuum over silica gel.
 

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Related Parent Nucleus of
[ 2555-37-5 ]

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