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Chemical Structure| 258516-82-4 Chemical Structure| 258516-82-4

Structure of 258516-82-4

Chemical Structure| 258516-82-4

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Product Details of [ 258516-82-4 ]

CAS No. :258516-82-4
Formula : C13H19ClO
M.W : 226.74
SMILES Code : CC(C1=C(OCCl)C(C(C)C)=CC=C1)C
MDL No. :MFCD09833643

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Application In Synthesis of [ 258516-82-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 258516-82-4 ]

[ 258516-82-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 258516-82-4 ]
  • [ 27425-92-9 ]
  • C34H62O12 [ No CAS ]
YieldReaction ConditionsOperation in experiment
60% General procedure: (Using the synthesis of acetal 1a as an example). Under the atmosphere of N2, to a suspension of NaH (645 mg, 60% dispersed in mineral oil, 16.2 mmol) in THF (30 mL) at 0 oC was slowly added a solution of M-PEG 5 (1.1 g, 9.0 mmol) in THF (20 mL). After the addition, the stirring mixture was warmed to rt. The mixture was stirred for 30 min and a solution of chloromethyl aryl ether 13 (3.1 g, 13.5 mmol) in THF (20 mL) was added. The resulting mixture was stirred for 12 h at rt, the solution was concentrated under vacuum and the residue was purified by column chromatography on silica gel (CH2Cl2/MeOH = 50/1) to give acetal 1a as clear oil (1.2 g, 44% yield, 99.9% pure (HPLC), Fig. S2).
 

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