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Chemical Structure| 269409-70-3 Chemical Structure| 269409-70-3
Chemical Structure| 269409-70-3

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Calum Gibb ; Jordan Hobbs ; Diana Nikolova ; Tom Raistrick ; Helen Gleeson ; Richard Mandle

Abstract: Spontaneous symmetry breaking and emergent polar order are each of fundamental importance to a range of scientific disciplines, as well as generating rich phase behaviour in liquid crystals (LCs). Here, we show the union of these phenomena to lead to two previously undiscovered polar liquid states of matter. Both phases have a lamellar structure with an inherent polar ordering of their constituent molecules. The first of these phases is characterised by polar order and a local tilted structure; the tilt direction precesses about a helix orthogonal to the layer normal, the period of which is such that we observe selective reflection of light. The second new phase type is anti-ferroelectric, with the constituent molecules aligning orthogonally to the layer normal. This has led us to term the phases the SmC_P^H and SmAAF phases, respectively. Further to this, we obtain room temperature ferroelectric nematic (NF) and SmC_P^Hphases via binary mixture formulation of the novel materials described here with a standard NF compound (DIO), with the resultant materials having melting points (and/or glass transitions) which are significantly below ambient temperature.

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Product Details of 4-Hydroxyphenylboronic acid pinacol ester

CAS No. :269409-70-3
Formula : C12H17BO3
M.W : 220.07
SMILES Code : OC1=CC=C(B2OC(C)(C)C(C)(C)O2)C=C1
MDL No. :MFCD02093756
InChI Key :BICZJRAGTCRORZ-UHFFFAOYSA-N
Pubchem ID :2734624

Safety of 4-Hydroxyphenylboronic acid pinacol ester

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 4-Hydroxyphenylboronic acid pinacol ester

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 269409-70-3 ]
  • Downstream synthetic route of [ 269409-70-3 ]

[ 269409-70-3 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 1895-39-2 ]
  • [ 269409-70-3 ]
  • [ 1333222-12-0 ]
YieldReaction ConditionsOperation in experiment
53% at 80℃; Sealed tube In a sealed tube was added 2-hydroxy-5-(4,4,5,5-tetramethyl-1 ,3,2-dioxaborolan-2-yl)pyridine (300 mg, 1.357 mmol), sodium chlorodifluoroacetate (320 mg, 2.036 mmol) in acetonitrile (5 mL). This suspension was heated to 80°C and stirred overnight. The reaction mixture was cooled down to rt, diluted with EtOAc, washed with an aqueous solution of NaHC03 and brine. The organic layer dried over MgS04, filtered and evaporated. Purification by flash chromatography on silica gel (CH2CI2/MeOH, 95/5) gave the title compound (197 mg, 53percent yield). MS: 272.8 [M+H]+, Rt (6) = 3.12 min.
References: [1] Patent: WO2013/88404, 2013, A1, . Location in patent: Page/Page column 96.
 

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