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Chemical Structure| 26978-65-4 Chemical Structure| 26978-65-4

Structure of 26978-65-4

Chemical Structure| 26978-65-4

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Product Details of [ 26978-65-4 ]

CAS No. :26978-65-4
Formula : C2H5BrO3S
M.W : 189.03
SMILES Code : BrCCS(=O)(O)=O
MDL No. :MFCD08059352
InChI Key :OQFSYHWITGFERZ-UHFFFAOYSA-N
Pubchem ID :33662

Safety of [ 26978-65-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H314-H330
Precautionary Statements:P260-P280-P284-P301+P310-P305+P351+P338-P310
Class:8(6.1)
UN#:2923
Packing Group:

Application In Synthesis of [ 26978-65-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 26978-65-4 ]

[ 26978-65-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4263-52-9 ]
  • [ 26978-65-4 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; In ethanol; at 5 - 20℃; for 4h; Synthesis of intermediate II (1-delta-sulphoethyl,-2,3,3-trimethyl-5-sulphonamido indolenininium inner salt); [Show Image] 150 g of <strong>[4263-52-9]2-bromoethanesulfonic acid sodium salt</strong>, Fluka, 1,5 1 of ethanol are mixed together, the mixture is then cooled to 5C and 29,2 g of hydrochloric acid gas are bubbled through the mixture. After that, the mixture is brought back to RT and left under stirring for 4 hours. After filtration of sodium chloride, the mixture is concentrated to dryness under vacuum. 1,6 g of 2-bromoethanesulfonic acid, obtained with the method reported above, 1,3 g of intermediate I, 0,7 g of triethylamine and 5 ml of butirronitrile are mixed together and heated to reflux for 20 hours. The mixture is then cooled to rrom temperature and 15 ml of acetone are added. The solid product is vacuum filtered and washed with methanol and acetone. The reaction yield is 50%.
 

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