[ CAS No. 2715-70-0 ]

Name: 2715-70-0|9-Butyl-9H-purin-6-amine|97%
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Quality Control of [ 2715-70-0 ]

COA NMR CNMR HPLC LC-MS

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Product Details of [ 2715-70-0 ]

CAS No. :	2715-70-0	MDL No. :	MFCD18843695
Formula :	C₉H₁₃N₅	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	N/A
M.W :	191.23 g/mol	Pubchem ID :	-
Synonyms :

Calculated chemistry of of [ 2715-70-0 ]

Physicochemical Properties

Num. heavy atoms :	14
Num. arom. heavy atoms :	9
Fraction Csp3 :	0.44
Num. rotatable bonds :	3
Num. H-bond acceptors :	3.0
Num. H-bond donors :	1.0
Molar Refractivity :	55.41
TPSA :	69.62 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	No
P-gp substrate :	No
CYP1A2 inhibitor :	Yes
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-6.58 cm/s

Lipophilicity

Log Po/w (iLOGP) :	1.84
Log Po/w (XLOGP3) :	1.25
Log Po/w (WLOGP) :	1.22
Log Po/w (MLOGP) :	0.56
Log Po/w (SILICOS-IT) :	0.64
Consensus Log Po/w :	1.1

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	1.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-2.09
Solubility :	1.55 mg/ml ; 0.00811 mol/l
Class :	Soluble
Log S (Ali) :	-2.31
Solubility :	0.936 mg/ml ; 0.00489 mol/l
Class :	Soluble
Log S (SILICOS-IT) :	-2.59
Solubility :	0.496 mg/ml ; 0.00259 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	0.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.95

Safety of [ 2715-70-0 ]

Signal Word:	Warning	Class:
Precautionary Statements:	P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362	UN#:
Hazard Statements:	H315-H319	Packing Group:
GHS Pictogram:

Application In Synthesis of [ 2715-70-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 2715-70-0 ]

[ 2715-70-0 ] Synthesis Path-Downstream 1~32

1
[ 5444-83-7 ]
[ 2715-70-0 ]

Yield	Reaction Conditions	Operation in experiment
	With ethanol; ammonia

Reference： [1]Montgomery; Temple [Journal of the American Chemical Society, 1958, vol. 80, p. 409]

2
[ 2715-70-0 ]
[ 75-36-5 ]
N⁶-acetyl-9-butyladenine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
34%	With pyridine In dichloromethane for 2h; Ambient temperature;

Reference： [1]Nowick, James S.; Chen, Jenny S.; Noronha, Glenn [Journal of the American Chemical Society, 1993, vol. 115, # 17, p. 7636 - 7644]

3
[ 109-65-9 ]
[ 134461-75-9 ]
[ 2715-70-0 ]

Yield	Reaction Conditions	Operation in experiment
85%	With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h;
85%	With potassium carbonate In N,N-dimethyl-formamide at 20℃;
85%	With potassium carbonate In N,N-dimethyl-formamide

81%	With potassium carbonate In N,N-dimethyl-formamide at 25℃; for 96h; Inert atmosphere;
64%	Stage #1: adenine With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere; Stage #2: 1-bromo-butane In N,N-dimethyl-formamide at 20℃; Inert atmosphere;	4.1.1.1 General procedure used for preparing 9-alkylated adenine General procedure: To a suspension of adenine in dry DMF, NaH (1.1equiv) was added under argon. The mixture was stirred at rt for 1h then the alkylating agent (1.05equiv) was added and the mixture was stirred until complete reaction.
	With sodium hydride 1.) DMF, 1 h, 2.) DMF, 16 h; Yield given. Multistep reaction;
	With potassium carbonate In dimethyl sulfoxide at 23℃; for 48h;	2.7 Synthesis of n-butyl adenine (nBA) guest molecule Adenine (6.05 g, 44.8 mmol), 1-bromobutane (6.16 g, 45.0 mmol), potassium carbonate (8.33 g, 60.3 mmol), and DMSO (60 mL) were added to a 250-mL round-bottomed flask. The resulting solution was stirred for 48 h at 23 °C and then poured into 600 mL water. The aqueous solution was extracted three times with 100 mL DCM and then the organic layer was washed three times with 100 mL water. The organic layer was dried over magnesium sulfate and concentrated in vacuo to obtain a solid. The product was obtained as a white solid after recrystallization from chloroform:hexanes. 1H NMR (400 MHz, CDCl3): 0.96 ppm (t, 3H, Ha), 1.37 ppm (m, 2H, Hb), 1.88 ppm (p, 2H, Hc), 4.20 ppm (t, 2H, Hd), 5.67 ppm (s, 2H, He), 7.79 ppm (s, 1H, Hf), 8.37 ppm (s, 1H, Hg) (Fig. S5).

Reference： [1]Ghosh, Kumaresh; Sen, Tanushree; Fröhlich, Roland [Tetrahedron Letters, 2007, vol. 48, # 39, p. 7022 - 7026]
[2]Location in patent: scheme or table Ghosh, Kumaresh; Sen, Tanushree [Tetrahedron Letters, 2008, vol. 49, # 50, p. 7204 - 7208]
[3]Location in patent: scheme or table Ghosh, Kumaresh; Sen, Tanushree [Beilstein Journal of Organic Chemistry, 2010, vol. 6]
[4]Location in patent: experimental part Lambertucci, Catia; Antonini, Ippolito; Buccioni, Michela; Dal Ben, Diego; Kachare, Dhuldeo D.; Volpini, Rosaria; Klotz, Karl-Norbert; Cristalli, Gloria [Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 7, p. 2812 - 2822]
[5]Boucherle, Benjamin; Bertrand, Johanna; Maurin, Bruno; Renard, Brice-Loïc; Fortuné, Antoine; Tremblier, Brice; Becq, Frédéric; Norez, Caroline; Décout, Jean-Luc [European Journal of Medicinal Chemistry, 2014, vol. 83, p. 455 - 465]
[6]Nowick, James S.; Chen, Jenny S.; Noronha, Glenn [Journal of the American Chemical Society, 1993, vol. 115, # 17, p. 7636 - 7644]
[7]Tamami, Mana; Hemp, Sean T.; Zhang, Keren; Zhang, Mingqiang; Moore, Robert B.; Long, Timothy E. [Polymer, 2013, vol. 54, # 6, p. 1588 - 1595]

4
[ 2715-70-0 ]
C₉H₁₁ClN₅^(1-)*Na⁽¹⁺⁾ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide; tert-butylhypochlorite In methanol

Reference： [1]Dress, K. Ruprecht; Goossen, Lukas J.; Liu, Hong; Jerina, Donald M.; Sharpless, K. Barry [Tetrahedron Letters, 1998, vol. 39, # 42, p. 7669 - 7672]

5
[ 2715-70-0 ]
[ 98-88-4 ]
N₁-(9-butyl-9H-6-purinyl)benzamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
74%	In pyridine at 100℃; for 1h;

Reference： [1]Crisp, Geoffrey T.; Jiang, Yu-Lin [Tetrahedron, 1999, vol. 55, # 2, p. 549 - 560]

6
[ 2715-70-0 ]
[ 173314-95-9 ]
4-butoxy-N₂,N₆-di(9-butyl-9H-6-purinyl)-2,6-pyridinedicarboxamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With thionyl chloride 1.) reflux, 0.5 h, 2.) pyridine, 90 deg C, 1 h; Yield given; Multistep reaction;

Reference： [1]Crisp, Geoffrey T.; Jiang, Yu-Lin [Tetrahedron, 1999, vol. 55, # 2, p. 549 - 560]

8
[ 2715-70-0 ]
[ 202136-43-4 ]

Yield	Reaction Conditions	Operation in experiment
77%	With bromine; sodium acetate; acetic acid In tetrahydrofuran; methanol at 20℃; for 0.5h;
41%	With N-Bromosuccinimide In N,N-dimethyl-formamide at 20℃; for 40h; Inert atmosphere;

Reference： [1]Zhang, Lin; Fan, Junhua; Vu, Khang; Hong, Kevin; Le Brazidec, Jean-Yves; Shi, Jiandong; Biamonte, Marco; Busch, David J.; Lough, Rachel E.; Grecko, Roy; Ran, Yingqing; Sensintaffar, John L.; Kamal, Adeela; Lundgren, Karen; Burrows, Francis J.; Mansfield, Robert; Timony, Gregg A.; Ulm, Edgar H.; Kasibhatla, Srinivas R.; Boehm, Marcus F. [Journal of Medicinal Chemistry, 2006, vol. 49, # 17, p. 5352 - 5362]
[2]Location in patent: experimental part Lambertucci, Catia; Antonini, Ippolito; Buccioni, Michela; Dal Ben, Diego; Kachare, Dhuldeo D.; Volpini, Rosaria; Klotz, Karl-Norbert; Cristalli, Gloria [Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 7, p. 2812 - 2822]

9
[ 134461-75-9 ]
[ 2715-70-0 ]

Yield	Reaction Conditions	Operation in experiment
95%	With caesium carbonate In N,N-dimethyl-formamide for 16h;

10
[ 2715-70-0 ]
[ 10387-13-0 ]
C₃₄H₃₆N₁₀ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
9%	Stage #1: 9-butyladenine With sodium hydride In tetrahydrofuran for 3h; Heating; Stage #2: 9,1-bis(chloromethyl)anthracene In tetrahydrofuran for 10h; Further stages.;

Reference： [1]Ghosh, Kumaresh; Sen, Tanushree; Fröhlich, Roland [Tetrahedron Letters, 2007, vol. 48, # 39, p. 7022 - 7026]

11
[ 2715-70-0 ]
[ 24463-19-2 ]
C₂₄H₂₃N₅ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
60%	Stage #1: 9-butyladenine With sodium hydride In tetrahydrofuran for 3h; Heating; Stage #2: anthracenylmethyl chloride In tetrahydrofuran for 6h; Heating; Further stages.;
60%	With sodium hydride In tetrahydrofuran; N,N-dimethyl-formamide Reflux;

12
[ 2715-70-0 ]
8-(benzothiazol-2-ylsulfanyl)-9-butyl-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 78 percent / dimethylformamide / 6 h / 130 °C

13
[ 2715-70-0 ]
9-butyl-8-(7-chlorothiazolo[4,5-c]pyridin-2-ylsulfanyl)-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 86 percent / dimethylformamide / 6 h / 130 °C

14
[ 2715-70-0 ]
9-butyl-8-(6-chlorobenzothiazol-2-ylsulfanyl)-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 77 percent / dimethylformamide / 6 h / 130 °C

15
[ 2715-70-0 ]
9-butyl-8-(4-chlorobenzothiazol-2-ylsulfanyl)-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 72 percent / dimethylformamide / 6 h / 130 °C

16
[ 2715-70-0 ]
9-butyl-8-(5-chlorobenzothiazol-2-ylsulfanyl)-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 75 percent / dimethylformamide / 6 h / 130 °C

17
[ 2715-70-0 ]
9-butyl-8-(7-fluorobenzothiazol-2-ylsulfanyl)-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 73 percent / dimethylformamide / 6 h / 130 °C

18
[ 2715-70-0 ]
9-butyl-8-(7-methylbenzothiazol-2-ylsulfanyl)-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 79 percent / dimethylformamide / 6 h / 130 °C

19
[ 2715-70-0 ]
8-(7-bromobenzothiazol-2-ylsulfanyl)-9-butyl-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 80 percent / dimethylformamide / 6 h / 130 °C

20
[ 2715-70-0 ]
9-butyl-8-(7-chlorobenzothiazol-2-ylsulfanyl)-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 76 percent / dimethylformamide / 6 h / 130 °C

21
[ 2715-70-0 ]
9-butyl-8-(7-methoxybenzothiazol-2-ylsulfanyl)-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 80 percent / dimethylformamide / 6 h / 130 °C

22
[ 2715-70-0 ]
8-(7-bromothiazolo[5,4-b]pyridin-2-ylsulfanyl)-9-butyl-9H-purine-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 81 percent / dimethylformamide / 6 h / 130 °C

23
[ 2715-70-0 ]
9-butyl-8-(6,7-dichlorobenzothiazol-2-ylsulfanyl)-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 81 percent / dimethylformamide / 6 h / 130 °C

24
[ 2715-70-0 ]
9-butyl-8-(7-ethoxybenzothiazol-2-ylsulfanyl)-9H-purin-6-ylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: 77 percent / HOAc; Br₂; NaOAc / tetrahydrofuran; methanol / 0.5 h / 20 °C 2.1: potassium tert-butoxide / dimethylformamide / 0.25 h / 20 °C 2.2: 78 percent / dimethylformamide / 6 h / 130 °C

25
[ 2715-70-0 ]
1-(9-Butyl-9H-purin-6-ylamino)-2-methyl-1-phenyl-propan-2-ol [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: 1.) t-BuOCl; 2.) aq. NaOH / methanol 2: (DHQ)2PHAL, K₂OsO₂(OH)4 / methanol; propan-1-ol / 50 °C

Reference： [1]Dress, K. Ruprecht; Goossen, Lukas J.; Liu, Hong; Jerina, Donald M.; Sharpless, K. Barry [Tetrahedron Letters, 1998, vol. 39, # 42, p. 7669 - 7672]

26
[ 2715-70-0 ]
(1S,2R)-1-(9-Butyl-9H-purin-6-ylamino)-1,2,3,4-tetrahydro-naphthalen-2-ol [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: 1.) t-BuOCl; 2.) aq. NaOH / methanol 2: (DHQ)2PHAL, K₂OsO₂(OH)4 / methanol; propan-1-ol / 50 °C

Reference： [1]Dress, K. Ruprecht; Goossen, Lukas J.; Liu, Hong; Jerina, Donald M.; Sharpless, K. Barry [Tetrahedron Letters, 1998, vol. 39, # 42, p. 7669 - 7672]

27
[ 2715-70-0 ]
(1R,2R)-2-(9-Butyl-9H-purin-6-ylamino)-1,2-diphenyl-ethanol [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: 1.) t-BuOCl; 2.) aq. NaOH / methanol 2: (DHQ)2PHAL, K₂OsO₂(OH)4 / methanol; propan-1-ol / 50 °C

Reference： [1]Dress, K. Ruprecht; Goossen, Lukas J.; Liu, Hong; Jerina, Donald M.; Sharpless, K. Barry [Tetrahedron Letters, 1998, vol. 39, # 42, p. 7669 - 7672]

28
[ 542-69-8 ]
[ 134461-75-9 ]
[ 2715-70-0 ]

Yield	Reaction Conditions	Operation in experiment
51%	With caesium carbonate In N,N-dimethyl-formamide at 50℃;
51%	With caesium carbonate In N,N-dimethyl-formamide at 50℃;

Reference： [1]Klein, Suzane M.; Zhang, Cungen; Jiang, Yu Lin [Tetrahedron Letters, 2008, vol. 49, # 16, p. 2638 - 2641]
[2]Location in patent: experimental part Lamale, Bassam; Henry, William P.; Daniels, Lee M.; Zhang, Cungen; Klein, Suzane M.; Jiang, Yu Lin [Tetrahedron, 2009, vol. 65, # 1, p. 62 - 69]

29
[ 2715-70-0 ]
[ 86-84-0 ]
[ 1093101-38-2 ]

Yield	Reaction Conditions	Operation in experiment
45%	In tetrahydrofuran Reflux;

Reference： [1]Location in patent: scheme or table Ghosh, Kumaresh; Sen, Tanushree [Tetrahedron Letters, 2008, vol. 49, # 50, p. 7204 - 7208]

30
[ 2715-70-0 ]
3-chloro-β-nitrostyrene [ No CAS ]
[ 1547236-52-1 ]

Yield	Reaction Conditions	Operation in experiment
64%	With copper(I) bromide; Trimethylacetic acid In dimethyl sulfoxide at 130℃; for 24h;

Reference： [1]Xie, Ming-Sheng; Chu, Zhi-Liang; Niu, Hong-Ying; Qu, Gui-Rong; Guo, Hai-Ming [Journal of Organic Chemistry, 2014, vol. 79, # 3, p. 1093 - 1099]

31
[ 2715-70-0 ]
[ 101671-01-6 ]
[ 1547236-54-3 ]

Yield	Reaction Conditions	Operation in experiment
76%	With copper(I) bromide; Trimethylacetic acid In dimethyl sulfoxide at 130℃; for 24h;

Reference： [1]Xie, Ming-Sheng; Chu, Zhi-Liang; Niu, Hong-Ying; Qu, Gui-Rong; Guo, Hai-Ming [Journal of Organic Chemistry, 2014, vol. 79, # 3, p. 1093 - 1099]

32
[ 2715-70-0 ]
trans-1-(4-fluorophenyl)-2-nitro-ethene [ No CAS ]
[ 1547236-56-5 ]

Yield	Reaction Conditions	Operation in experiment
78%	With copper(I) bromide; Trimethylacetic acid In dimethyl sulfoxide at 130℃; for 24h;

Reference： [1]Xie, Ming-Sheng; Chu, Zhi-Liang; Niu, Hong-Ying; Qu, Gui-Rong; Guo, Hai-Ming [Journal of Organic Chemistry, 2014, vol. 79, # 3, p. 1093 - 1099]

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P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
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Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 2715-70-0 ]

Quality Control of [ 2715-70-0 ]

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Product Details of [ 2715-70-0 ]

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Physicochemical Properties

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Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

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Application In Synthesis of [ 2715-70-0 ]

[ 2715-70-0 ] Synthesis Path-Downstream 1~32

Related Functional Groups of [ 2715-70-0 ]

Amines

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Purines

Precautionary Statements-General

Prevention

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Physical hazards

Health hazards

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Inquiry

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[ 2715-70-0 ]

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