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Chemical Structure| 2843-19-8 Chemical Structure| 2843-19-8

Structure of 2843-19-8

Chemical Structure| 2843-19-8

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Product Details of [ 2843-19-8 ]

CAS No. :2843-19-8
Formula : C5H12ClNO2
M.W : 153.61
SMILES Code : O=C(O)C(C)(C)CN.[H]Cl
MDL No. :MFCD11858331

Safety of [ 2843-19-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 2843-19-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2843-19-8 ]

[ 2843-19-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 24424-99-5 ]
  • [ 2843-19-8 ]
  • [ 180181-02-6 ]
YieldReaction ConditionsOperation in experiment
95% With potassium hydroxide; In 1,4-dioxane; at 20℃; for 20h; 1 M KOH (52.08 ml, 52.08 mmol) was added to a mixture of 3-amino-2,2-dimethylpropanoic acid hydrochloride (4 g , 26.04 mmol) and BoHCI and extracted with EtOAc (4 x 50 ml). The combined organic layers were washed with brine (50 ml), dried (Na2S04), filtered and evaporated to give the title compound (5.38 g, 95%) as a white solid . Compound will be used in the next step without further purification. 1 H-NMR (CDCI3, 250 MHz): d[ppm]= 5.01 (s, 1 H), 3.29 - 3.18 (m, 2H), 1 .45 (d, 9H), 1 .23 (s, 6H)
 

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