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Chemical Structure| 28504-80-5 Chemical Structure| 28504-80-5

Structure of 28504-80-5

Chemical Structure| 28504-80-5

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Product Details of [ 28504-80-5 ]

CAS No. :28504-80-5
Formula : C8H4Br2S3
M.W : 356.12
SMILES Code : BrC1=C(SC2=C(Br)C=CS2)SC=C1

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Application In Synthesis of [ 28504-80-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 28504-80-5 ]

[ 28504-80-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 28504-80-5 ]
  • [ 34907-53-4 ]
  • C17H15BS3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
83% DTTB 2 synthesis: weighing the compound 3, 3 '- dibromo - 2, 2' double-thiophene thioether (2.02g, 5 . 67mmol, 1 . 00 equiv) by adding 250 ml of bottle in the reaction, in the N2Under the protection of adding 50 ml ethyl ether to fully dissolve, the reaction system is transferred to the -78 C stirring 30 minutes. In the same temperature, slowly added dropwise n-BUli(2.5M in hexane, 12 . 00mmol, 2 . 11 equiv), stirring 1 hour later, the mixture slowly rose to 10 C, then slowly adding mi Ji boric acid dimethyl ester (1.32g, 6 . 87mmol, 1 . 21 equiv), the reaction system is gradually raised to room temperature, stirring overnight. 2nd day, water quenching, ethyl acetate extraction three times, the combined organic phase, adding anhydrous magnesium sulfate drying, filtering, the Rotavapor for removing solvent, chromatography method for the purification of the target product, mobile phase: petroleum ether (PE), purifying the crude product by silica gel column chromatography to obtain white solid product 2757 mg, yield=41%.
 

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