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Chemical Structure| 288251-78-5 Chemical Structure| 288251-78-5

Structure of 288251-78-5

Chemical Structure| 288251-78-5

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Product Details of [ 288251-78-5 ]

CAS No. :288251-78-5
Formula : C12H15N3O
M.W : 217.27
SMILES Code : N#CC1=CC(N)=CC=C1N2CCC(O)CC2
MDL No. :MFCD14617263

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Application In Synthesis of [ 288251-78-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 288251-78-5 ]

[ 288251-78-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 288251-78-5 ]
  • [ 19156-54-8 ]
  • [ 398137-02-5 ]
YieldReaction ConditionsOperation in experiment
EXAMPLE 18 N-[3-cyano-4-(4-hydroxypiperidin-1-yl)phenyl]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide By the reaction and treatment in the same manner as in Example 6 using <strong>[19156-54-8]4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid</strong> (1.2 g) and 5-amino-2-(4-hydroxypiperidin-1-yl)benzonitrile (1.3 g), the title compound (1.2 g) was obtained. melting point: 172-173 C. 1H-NMR (270 MHz, DMSO-d6)delta:1.55-1.63 (2H, m), 1.64-1.80 (4H, m), 1.86-1.90 (2H, m), 2.7-2.8 (4H, M), 2.87 (2H, t, J=9.2 Hz), 3.29-3.34 (2H, m), 3.65-3.68 (1H, m), 4.70 (1H, m), 6.98 (1H, d, J=8.6 Hz), 7.83 (1H, dd, J=2.6, 8.6 Hz), 7.92 (1H, s), 8.03 (1H, d, J=2.6 Hz), 10.10 (1H, S).
 

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