Home Cart Sign in  
Chemical Structure| 289651-72-5 Chemical Structure| 289651-72-5

Structure of 289651-72-5

Chemical Structure| 289651-72-5

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 289651-72-5 ]

CAS No. :289651-72-5
Formula : C11H7FN4O
M.W : 230.20
SMILES Code : O=C1C2=C(N(C3=CC=C(F)C=C3)N=C2)N=CN1
MDL No. :MFCD06673456

Safety of [ 289651-72-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 289651-72-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 289651-72-5 ]

[ 289651-72-5 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 51516-70-2 ]
  • [ 289651-72-5 ]
  • 2
  • [ 64-18-6 ]
  • [ 51516-70-2 ]
  • [ 289651-72-5 ]
YieldReaction ConditionsOperation in experiment
89% for 12h;Reflux; General procedure: A mixture of 5-amino-1-phenyl-1H-pyrazole-4-carbonitriles (7-12)(0.01 mol) and 20 mL of formic acid was stirred and allowed to reflux for 12 h. The reaction mixture was poured into 50 mL of ice-cold water. The precipitate was collected by filtration and washed with water to produce 13-18 in 68-89% yield.
  • 3
  • [ 64-18-6 ]
  • [ 51516-70-2 ]
  • [ 289651-72-5 ]
YieldReaction ConditionsOperation in experiment
89% for 12h;Reflux; General procedure: A mixture of 5-amino-1-phenyl-1H-pyrazole-4-carbonitrile(10a-c) (0.01 mol) and 20 mL of formic acid was stirredand allowed to reflux for 12 h. The reaction mixture waspoured into 50 mL of ice-cold water. The precipitate wascollected by filtration and washed with water to afford11a-c in 73-89% yield.1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol(11a)Yield: 89%. MP: > 300 C. IR (cm-1): 3113; 1724; 1597;1510; 1233. 1H NMR (400 MHz, DMSO-d6, TMS, delta in p.p.m.): 7.44-7.40 (m; 2 H; H3?, H5?); 8.08-8.04 (m; 2 H; H2?,H6?); 8.21 (d; 1 H; H6; J = 3.8 Hz); 8.33 (s; 1 H; H3); 12.47(s; 1 H; OH). 13C NMR (100 MHz, DMSO-d6, TMS, delta in p.p.m.): 107.5 (C3a); 116.1 (d; J = 22.9 Hz; C3?, C5?); 123.8(d; J = 8.6 Hz; C2?, C6?); 134.6 (d; J = 2.7 Hz; C1?); 136.0(C3); 148.9 (C6); 151.7 (C7a); 157.1 (C4); 160.6 (d; J =242.8 Hz; C4?)19F NMR (376 MHz, DMSO-d6, TMS, delta inppm): -114.88. EI [M + 1]+ 231.07.
 

Historical Records

Technical Information

Categories