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[ CAS No. 29113-34-6 ]

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Chemical Structure| 29113-34-6
Chemical Structure| 29113-34-6
Structure of 29113-34-6 * Storage: {[proInfo.prStorage]}

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Product Details of [ 29113-34-6 ]

CAS No. :29113-34-6 MDL No. :MFCD02059339
Formula : C9H6N2O3 Boiling Point : 427.6±28.0°C at 760 mmHg
Linear Structure Formula :- InChI Key :-
M.W :190.16 g/mol Pubchem ID :-
Synonyms :

Safety of [ 29113-34-6 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 29113-34-6 ]

  • Downstream synthetic route of [ 29113-34-6 ]

[ 29113-34-6 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 29113-34-6 ]
  • [ 24157-18-4 ]
  • N-(3-(4-benzylpiperidin-1-yl)propyl)-4-oxo-3,4-dihydroquinazoline-2-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20℃; for 1h; General procedure: To the stirred solution of 4-oxo-3, 4-dihydroquinazoline-2-carboxylic acid (0.1 g, 0.0005 mol) in N,N-dimethyl formamideDMF, N-phenyl piperzine derivatives (0.0005 mol),or 3-(4-phenylpiperazin-1-yl)propan-1-amine derivatives(9a-g, 0.0005 mol) were added at room temperature, followedby the addition of EDC HCl (0.0006 mol) and HOBt(0.0006 mol) and the mixture was stirred for 1 h. Aftercompletion of the reaction (TLC analysis), small amount ofice cold water (10 mL) was added to the reaction mixtureand then extracted with chloroform (2 × 10 mL). Thechloroform layer was separated, dried over Na2SO4, andevaporated under vacuum to give corresponding hybrids(10a-g, 11a-g) in good yields.
  • 2
  • [ 29113-34-6 ]
  • [ 30459-17-7 ]
  • 2-(4-(4-(trifluoromethyl) phenyl) piperazine-1-carbonyl)quinazolin-4(3H)-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20℃; for 1h; General procedure: To the stirred solution of 4-oxo-3, 4-dihydroquinazoline-2-carboxylic acid (0.1 g, 0.0005 mol) in N,N-dimethyl formamideDMF, N-phenyl piperzine derivatives (0.0005 mol),or 3-(4-phenylpiperazin-1-yl)propan-1-amine derivatives(9a-g, 0.0005 mol) were added at room temperature, followedby the addition of EDC HCl (0.0006 mol) and HOBt(0.0006 mol) and the mixture was stirred for 1 h. Aftercompletion of the reaction (TLC analysis), small amount ofice cold water (10 mL) was added to the reaction mixtureand then extracted with chloroform (2 × 10 mL). Thechloroform layer was separated, dried over Na2SO4, andevaporated under vacuum to give corresponding hybrids(10a-g, 11a-g) in good yields.
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