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Chemical Structure| 29241-62-1 Chemical Structure| 29241-62-1
Chemical Structure| 29241-62-1

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Product Details of 5-Bromo-6-chloronicotinic acid

CAS No. :29241-62-1
Formula : C6H3BrClNO2
M.W : 236.45
SMILES Code : O=C(O)C1=CN=C(Cl)C(Br)=C1
MDL No. :MFCD01927098
InChI Key :DXEUARPQHJXMII-UHFFFAOYSA-N
Pubchem ID :285433

Safety of 5-Bromo-6-chloronicotinic acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of 5-Bromo-6-chloronicotinic acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 29241-62-1 ]

[ 29241-62-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17282-03-0 ]
  • [ 29241-62-1 ]
YieldReaction ConditionsOperation in experiment
With potassium permanganate; In water; (a) Preparation of 3-bromo-2-chloro-5-pyridine carboxylic acid 3-Bromo-2-chloro-5-methylpyridine (30 g) in water (650 ml) containing potassium permanganate (60 g) was stirred and heated under reflux for 3 hours. Further potassium permanganate (20 g) was then added and the mixture heated and stirred for another 21/2 hours. The mixture was steam-distilled to remove unchanged starting material, and then filtered while hot. The residue was washed with hot water. The filtrate and washings were cooled and acidified with concentrated hydrochloric acid. The solid which separated was extracted with ether. The ether extract was dried and evaporated to give 3-bromo-2-chloropyridine-5-carboxylic acid.
 

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