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Chemical Structure| 297165-32-3 Chemical Structure| 297165-32-3

Structure of 297165-32-3

Chemical Structure| 297165-32-3

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Product Details of [ 297165-32-3 ]

CAS No. :297165-32-3
Formula : C11H16N2O4S
M.W : 272.32
SMILES Code : O=C(C1=CSC(CNC(OC(C)(C)C)=O)=N1)OC
MDL No. :MFCD23378468

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Application In Synthesis of [ 297165-32-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 297165-32-3 ]

[ 297165-32-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 7425-63-0 ]
  • [ 89226-13-1 ]
  • [ 297165-32-3 ]
YieldReaction ConditionsOperation in experiment
56% With calcium carbonate; In ethanol; at 20℃;Inert atmosphere; To a solution of 5 (666 mg, 3.5 mmol, 1 equiv.) in ethanol (10 mL), methyl-3-bromopyruvate (410 muL, 3.85 mmol, 1.1 equiv.) and calcium carbonate (189 mg, 1.89 mmol, 0.54 equiv.) were added. The reaction mixture was stirred under argon at rt overnight. The reaction mixture was evaporated under reduced pressure. The residue was partitioned between CHCl3 and saturated NaHCO3 solution. The organic layer was then washed once with water. The combined organic layers were dried over MgSO4, filtered and concentrated in vacuo. The crude material was purified by flash chromatography (Hexane/EtOAc 7/3) to afford 7 as a yellow solid (585 mg, 56%)
  • 2
  • [ 67-56-1 ]
  • [ 868-59-7 ]
  • [ 85363-04-8 ]
  • [ 297165-32-3 ]
  • [ 96929-05-4 ]
 

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