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Chemical Structure| 299417-31-5 Chemical Structure| 299417-31-5

Structure of 299417-31-5

Chemical Structure| 299417-31-5

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Product Details of [ 299417-31-5 ]

CAS No. :299417-31-5
Formula : C7H12N2S
M.W : 156.25
SMILES Code : NC1=NC=C(C(C)(C)C)S1
MDL No. :MFCD02170355
InChI Key :YPVUVTIITAMAPQ-UHFFFAOYSA-N
Pubchem ID :676485

Safety of [ 299417-31-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P280-P305+P351+P338-P310

Application In Synthesis of [ 299417-31-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 299417-31-5 ]

[ 299417-31-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 207981-46-2 ]
  • [ 299417-31-5 ]
  • [ 1232169-34-4 ]
YieldReaction ConditionsOperation in experiment
71% With triethylamine; In dichloromethane; at 20℃; for 6h; Example 9; N-IY2Z)-3-butyl-5-tert-butyl- 1.3-thiazol-2(3H)-ylidenel-2- (IY2SV 1 -methylpyrrolidin-2- yllmethoxyl -5 -(trifluoromethyl)benzamide; Example 9A; N-r(2Z)-5-fert-butyl-l,3-thiazol-2(3H)-ylidenel-2-fluoro-5-(trifluoromethyl)benzamide; A mixture of 5-tert-butylthiazol-2-amine (1.93 g, 12.3 mmol) and triethylamine (3.44 mL, 2.46 mmol) in dichloromethane (50 mL) was treated with 2-fluoro-5- (trifluoromethyl)benzoyl chloride (Alfa,1.87 mL,12.3 mmol) and stirred at room temperature for 6 hours. The reaction mixture was washed with brine, dried (MgSC^), filtered, and concentrated. The residue was purified using an Analogix Intelliflash280 (SiO2, 0-50 % ethyl acetate in hexanes) to give the title compound (3 g, 71% yield). MS (DCI/NΗ3) m/z 347 (M+H)+.
 

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