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Chemical Structure| 302776-68-7 Chemical Structure| 302776-68-7
Chemical Structure| 302776-68-7

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Synonyms: DHHB

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Product Details of Diethylamino hydroxybenzoyl hexyl benzoate

CAS No. :302776-68-7
Formula : C24H31NO4
M.W : 397.51
SMILES Code : O=C(OCCCCCC)C1=CC=CC=C1C(C2=CC=C(N(CC)CC)C=C2O)=O
Synonyms :
DHHB
MDL No. :MFCD11616752
InChI Key :FDATWRLUYRHCJE-UHFFFAOYSA-N
Pubchem ID :10111431

Safety of Diethylamino hydroxybenzoyl hexyl benzoate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of Diethylamino hydroxybenzoyl hexyl benzoate

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 302776-68-7 ]

[ 302776-68-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3839-35-8 ]
  • [ 5809-23-4 ]
  • [ 302776-68-7 ]
YieldReaction ConditionsOperation in experiment
47.6% With potassium carbonate; In N,N-dimethyl-formamide; at 100 - 110℃; for 4h;Large scale; 2- (4-N, N-diethylamino-2-hydroxybenzoyl) benzoic acid (1.1 kg, 3.51 mol) synthesized in Preparation Example 1,Hexyl 4-methylbenzenesulfonate (1.1 kg, 4.22 mol), K2CO3 (0.9 kg, 7.02 mol) synthesized in Preparation Example 2-4 was stirred with 1.65 L of DMF.After raising the internal temperature to 100 ~ 110 and stirred for 4 hours, cooled and extracted with 3.5 L of ethyl acetate and 3.5 L of purified water.The separated organic layer was concentrated under reduced pressure after decolorizing for 1 hour using 5% charcoal at an internal temperature of 30-50 C.The concentrated residue was crystallized by the crystallization method of Example 3 to obtain the title compound (0.66 kg, 47.6%) in the form of crystalline particles.
 

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Technical Information

• Acyl Group Substitution • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Bouveault-Blanc Reduction • Bucherer-Bergs Reaction • Buchwald-Hartwig C-N Bond and C-O Bond Formation Reactions • Catalytic Hydrogenation • Chan-Lam Coupling Reaction • Clemmensen Reduction • Complex Metal Hydride Reductions • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Ester Cleavage • Fischer Indole Synthesis • Grignard Reaction • Henry Nitroaldol Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Lawesson's Reagent • Leuckart-Wallach Reaction • Mannich Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reactions with Organometallic Reagents • Reformatsky Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Carbodiimides and Related Reagents • Specialized Acylation Reagents-Ketenes • Specialized Acylation Reagents-Vilsmeier Reagent • Stobbe Condensation • Tebbe Olefination • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

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