Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
* Storage: {[proInfo.prStorage]}
CAS No. : | 30688-66-5 | MDL No. : | MFCD00167506 |
Formula : | C13H16O6 | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | XTVRQMKOKFFGDZ-ZLUZDFLPSA-N |
M.W : | 268.26 | Pubchem ID : | 147362 |
Synonyms : |
|
Num. heavy atoms : | 19 |
Num. arom. heavy atoms : | 6 |
Fraction Csp3 : | 0.46 |
Num. rotatable bonds : | 4 |
Num. H-bond acceptors : | 6.0 |
Num. H-bond donors : | 3.0 |
Molar Refractivity : | 63.99 |
TPSA : | 96.22 Ų |
GI absorption : | High |
BBB permeant : | No |
P-gp substrate : | No |
CYP1A2 inhibitor : | No |
CYP2C19 inhibitor : | No |
CYP2C9 inhibitor : | No |
CYP2D6 inhibitor : | No |
CYP3A4 inhibitor : | No |
Log Kp (skin permeation) : | -8.23 cm/s |
Log Po/w (iLOGP) : | 1.0 |
Log Po/w (XLOGP3) : | -0.41 |
Log Po/w (WLOGP) : | -0.94 |
Log Po/w (MLOGP) : | -0.77 |
Log Po/w (SILICOS-IT) : | 0.37 |
Consensus Log Po/w : | -0.15 |
Lipinski : | 0.0 |
Ghose : | None |
Veber : | 0.0 |
Egan : | 0.0 |
Muegge : | 0.0 |
Bioavailability Score : | 0.55 |
Log S (ESOL) : | -1.21 |
Solubility : | 16.4 mg/ml ; 0.061 mol/l |
Class : | Very soluble |
Log S (Ali) : | -1.15 |
Solubility : | 19.2 mg/ml ; 0.0714 mol/l |
Class : | Very soluble |
Log S (SILICOS-IT) : | -0.62 |
Solubility : | 64.6 mg/ml ; 0.241 mol/l |
Class : | Soluble |
PAINS : | 0.0 alert |
Brenk : | 1.0 alert |
Leadlikeness : | 0.0 |
Synthetic accessibility : | 4.06 |
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H302-H315-H319-H335 | Packing Group: | N/A |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
53.7% | With toluene-4-sulfonic acid In N,N-dimethyl-formamide at 60℃; for 6 h; | Glucose (1.00 g, 5.55 mmol) was added to a N, N-dimethylformamide solution (11.0 mL)It was heated to 60 ° C and dissolved.To this was added benzaldehyde dimethyl acetal (1.24 mL, 8.33 mmol),Paratoluenesulfonic acid monohydrate (10 mg) was added and the mixture was stirred at 60 ° C for 6 hours.The pressure reduction operation was carried out for 10 minutes every hour. After 6 hours, the reaction solution was evaporated under reduced pressure.The obtained residue was subjected to silica gel column chromatography, and as a white crystal from a fraction eluted with methanol / ethyl acetate (1/10)4,6-O-Benzyliden-D-glucopyranose (799.5 mg, 2.98 mmol, yield 53.7percent). As glucose, those of D - (+) - glucose (manufactured by Kanto Kagaku Co., Ltd.) were used. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
93.8% | With pyridine; dmap; at 20℃; for 1h; | A pyridine solution (26 mL) of <strong>[30688-66-5]4,6-O-benzyliden-D-glucopyranose</strong> (1.416 g, 5.28 mmol) Acetic anhydride (7.5 mL, 79.2 mmol) and 4-dimethylaminopyridine (193.0 mg, 1.58 mmol) were added,And the mixture was stirred at room temperature for 1 hour. After 1 hour, the reaction solution was evaporated under reduced pressure.The residue was subjected to silica gel column chromatography, and from an elution portion of ethyl acetate / hexane (1/1)As a white crystal, Acetyl 2,3-di-O-acetyl-4,6-O-benzyliden-D-glucopyranoside (1.954 g, 4.955 mmol, yield 93.8%) was obtained. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
82% | With sodium hydrogencarbonate; In tetrahydrofuran; water; for 36h;Reflux; | To a solution of 4,6-O-benzylidene-d-glucopyranose (2.68 g, 10.0 mmol) in 1:9 H2O-THF were added NaHCO3 (3.36 g, 4 equiv) and 2,4-pentadienone (2.0 g, 2 equiv). The reaction mixture was stirred at reflux temperature for 36 h, and then cooled to room temperature. The resultant mixture was filtered and the residue was washed well with CH2Cl2, which was then removed. The light-brown residue thus obtained was purified by column chromatography [3:7 hexane-EtOAc] to get the expected product: Yield: 2.526 g (82%) as a white solid; mp 142-144 C; 1H NMR (CDCl3): delta 7.46 (m, 2H, Ar-H), 7.35-7.37 (m, 3H, Ar-H), 5.47 (s, 1H, Ace-H), 4.78 (s, 1H, Sac-H), 4.22-4.27 (dd, J = 3.9 Hz, J = 10.2 Hz, 1H, Sac-H), 3.76-3.83 (ddd, J = 3.1 Hz, J = 7.5 Hz, J = 8.9 Hz, 1H, Sac-H), 3.68 (t, J = 8.4 Hz, 1H, Sac-H), 3.57-3.63 (m, 1H, Sac-H), 3.39-3.45 (m, 2H, Sac-H), 3.27 (t, J = 9.2 Hz, 1H, Sac-H), 2.79-2.85 (dd, J = 3.3 Hz, J = 16.2 Hz, 1H, Sac-H), 2.16 (s, 3H, -CH3). 13C NMR (CDCl3): delta 207.1, 137.0, 129.3, 128.4, 126.4, 101.8, 81.0, 76.0, 75.1, 74.1, 70.3, 68.7, 46.0, 31.0. Anal. Calcd for C16H20O6: C, 62.33; H, 6.54. Found: C, 61.97; H, 6.71. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
52% | In methanol; at 20℃; for 6h; | General procedure: To a solution of diamine 4a, 4b and 5a, 5b (1 mmol) in dry MeOH and 4,6-O-protected-d-glucopyranose (BGP, EGP, BzGP) (2 mmol) were added. After stirring at room temperature for given period of time, the reaction mixture was evaporated under reduced pressure. The crude product was slurried with silica gel and purified by column chromatography. For details (reaction time and yields of products) see refPreviewPlaceHolderTable 1. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
46% | In methanol; at 20℃; for 8h; | General procedure: To a solution of diamine 4a, 4b and 5a, 5b (1 mmol) in dry MeOH and 4,6-O-protected-d-glucopyranose (BGP, EGP, BzGP) (2 mmol) were added. After stirring at room temperature for given period of time, the reaction mixture was evaporated under reduced pressure. The crude product was slurried with silica gel and purified by column chromatography. For details (reaction time and yields of products) see refPreviewPlaceHolderTable 1. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
46% | In methanol; at 20℃; for 6h; | General procedure: To a solution of diamine 4a, 4b and 5a, 5b (1 mmol) in dry MeOH and 4,6-O-protected-d-glucopyranose (BGP, EGP, BzGP) (2 mmol) were added. After stirring at room temperature for given period of time, the reaction mixture was evaporated under reduced pressure. The crude product was slurried with silica gel and purified by column chromatography. For details (reaction time and yields of products) see refPreviewPlaceHolderTable 1. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
58% | In methanol; at 20℃; for 8h; | General procedure: To a solution of diamine 4a, 4b and 5a, 5b (1 mmol) in dry MeOH and 4,6-O-protected-d-glucopyranose (BGP, EGP, BzGP) (2 mmol) were added. After stirring at room temperature for given period of time, the reaction mixture was evaporated under reduced pressure. The crude product was slurried with silica gel and purified by column chromatography. For details (reaction time and yields of products) see refPreviewPlaceHolderTable 1. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
31% | Preparation of Compound 6A solution of hydrochloric acid salt 4 (1.50 g, 4.38 mmol) and triol 5 (1.17 g, 4.38 mmol) in MeOH (100 mL) and AcOH (2.10 g, 35.04 mmol) was stirred at room temperature for 2 h. Sodium cyanoborohydride (469 mg, 7.46 mmol) was added and the reaction mixture was stirred at room temperature overnight. Additional triol 5 (585 mg, 21.9 mmol) was added and the reaction mixture was stirred at room temperature for 4 h. The solvent was removed under vacuum. The residue was washed with saturated Na2CO3 (5.0 mL), azeotroped with MeOH, and purified by column chromatography (silica gel, 10:1 CH2Cl2/MeOH) to afford compound 6 (950 mg, 31%) as an off-white solid. C33H42N2O8 [M+H]+ 595. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
15% | AcOH (7 muIota, 0.1 mmol) was added to a solution of 2-[(3-amino-6-bromopyrazin-2- yl)formamido]methyl}-1 ,3-diethyl-6-t1-(piperidin-4-yl)-1 H-pyrazol-4-yl]-1 H-1 ,3- benzodiazol-3-ium hydrochloride iodide, Example 21 (60 mg, 0.083 mmol) and 4,6-0- benzylidene-D-glucopyranose (62 mg, 0.22 mmol) in anhydrous methanol (1.5 ml). The resulting solution was stirred at RT for 0.5 h then sodium cyanoborohydride (22 mg, 0.34 mmol) was added. The RM was stirred at RT for 4 h. More sodium cyanoborohydride (22 mg, 0.34 mmol) and <strong>[30688-66-5]4,6-O-benzylidene-D-glucopyranose</strong> (62 mg, 0.22 mmol) were added then the reaction was stirred at RT for 16 h. The reaction was added dropwise to saturated aq. NaHCOa solution (15 ml) then diluted with CH2CI2 (25 ml). CH2CI2:MeOH (2:1 , 10 ml) was added then the phases were separated. The organic phase was dried over Na2S04 and concentrated in vacuo to afford the intermediate as a light yellow solid (54 mg). A portion of the material thus obtained (50 mg, 0.057 mmol) was dissolved in aq. HCI solution (2 M, 4 ml). The reaction was stirred at RT for 3.5 h then concentrated in vacuo. The crude material was purified by flash column chromatography on C18 (12 g). The column was eluted with MeCN:H20 + 0.1 % formic acid using the following gradient (%MeCN, column volumes): 5%, 2 CV; 5-100%, 20 CV; 100%, 2 CV. The desired fractions were combined and lyophilised to afford the product as a white solid (7 mg, 15%).1H NMR (500 MHz, CD3OD) delta 8.52 (s, 1 H), 8.30 (s, 2H), 8.15 (s, 1 H), 8.04 (s, 1 H), 7.94 (s, 2H), 5.09 (s, 2H), 4.81 - 4.71 (m, 4H), 4.55 (s, 1 H), 4.31-4.25 (m, 1 H), 3.98 (q, J = 4.9 Hz, 1 H), 3.80 (dd, J = 11.6, 3.8 Hz, 2H), 3.76 - 3.61 (m, 3H), 3.22 (d, J = 10.6 Hz, 1 H), 2.77 - 2.64 (m, 2H), 2.54-2.35 (m, 2H), 2.20-2.14 (m, 4H), 1.60 - 1.52 (m, 6H). LC/MS (System C): m/z (ESI+) = 716 [M(79Br)+], 718 [M(8 Br)+] Rt = 1.35 min, UV purity = 100%. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
A mixture of <strong>[30688-66-5]4,6-O-benzylidene-D-glucopyranose</strong> (95%, 6.67 g, 23.6 mmol), 5-(2- aminoethoxy)-1 ,3-diethyl-2-[([(9/-/-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1 HA ,3- benzodiazol-3-ium hydrochloride chloride, Intermediate 86 (85%, 3.87 g, 5.91 mmol) and AcOH (1.35 ml, 23.6 mmol) in MeOH (100 ml) was stirred at RT for 0.5 h. NaCNBHs (1.48 g, 23.6 mmol) was added then the resulting mixture was stirred at RT for 20 h. More MeOH (40 ml) was added then the reaction was left to stir at RT for a further 24 h. More MeOH (80 ml) was added, then the reaction was retreated with 4,6-O-benzylidene-D- glucopyranose (95%, 1.60 g, 5.67 mmol), AcOH (0.34 ml, 5.94 mmol) and NaCNBHs (0.38 g, 6.05 mmol). The reaction was left to stir at RT for a further 92 h then added to saturated aqueous NaHCOs solution (250 ml). The resultant suspension was stirred at RT for 20 min. The solid was collected by filtration then washed with water and dried under vacuum to afford the product as a pale pink solid (6.43 g, 89%). LC/MS (System A): m/z (ESI+) = 990 [M+], 496 [(M+)+H+], Rt = 0.93 min, UV purity = 84%. | ||
A mixture of <strong>[30688-66-5]4,6-O-benzylidene-D-glucopyranose</strong> (95%, 6.67 g, 23.6 mmol), 5-(2- aminoethoxy)- 1, 3-diethyl-2-[([(9H-fluoren-9-yl)methoxy]carbonyl}am ino)methyl]-1 H- 1,3- benzodiazol-3-ium hydrochloride chloride, Intermediate 86 (85%, 3.87 g, 5.91 mmol) and AcOH (1.35 ml, 23.6 mmol) in MeOH (100 ml) was stirred at RT for 0.5 h. NaCNBH3(1.48 g, 23.6 mmol) was added then the resulting mixture was stirred at RT for 20 h.More MeOH (40 ml) was added then the reaction was left to stir at RT for a further 24 h.More MeOH (80 ml) was added, then the reaction was retreated with <strong>[30688-66-5]4,6-O-benzylidene-D-glucopyranose</strong> (95%, 1.60 g, 5.67 mmol), AcOH (0.34 ml, 5.94 mmol) and NaCNBH3(0.38 g, 6.05 mmol). The reaction was left to stir at RT for a further 92 h then added tosaturated aqueous NaHCO3 solution (250 ml). The resultant suspension was stirred atRT for 20 mm. The solid was collected by filtration then washed with water and driedunder vacuum to afford the product as a pale pink solid (6.43 g, 89%).1H NMR (500 MHz, CD3OD) O 7.76 (d, J= 8.5 Hz, 3H), 7.59 (d, J= 8.0 Hz, 2H), 7.53-7.49 (m, 2H), 7.47 - 7.43 (m, 4H), 7.37 - 7.34 (m, 3H), 7.33 - 7.25 (m, 1OH), 7.24 - 7.20(m, 2H), 5.50 (5, 2H), 4.63-4.48 (m, 7H), 4.30-4.16 (m, 6H), 4.08-4.03 (m, 2H), 3.99-3.93(m, 5H), 3.91 -3.86(m, 1H), 3.78-3.73(m, 3H), 3.67-3.56(m, 4H), 3.16- 3.06 (m, 2H), 3.00-2.93 (m, 2H), 2.85-2.77 (m, 2H), 1.49-1.37 (m, 6H). LCIMS (System A): m/z (ESl) = 990 [W], 496 [(M)+H], R = 0.93 mi UV purity = 84%. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
60% | alpha-picoline borane (0.861 g, 8.05 mmol) was added to a suspension of te/f-butyl Lambda/-(3- aminopropyl)-/V-methylcarbamate (0.505 g, 2.68 mmol) and 4,6-O-benzylidene-D- glucopyranose (2.88 g, 10.7 mmol) in MeOH (5 ml) . The mixture was heated at 60 C for 16 h. The reaction mixture was allowed to cool to RT then partitioned between EtOAc (20 ml) and water (20 ml). The phases were separated then the aqueous phase was extracted with EtOAc (20 ml). The combined organic phases were washed with water (20 ml) and 1 :1 water:brine (20 ml) then dried over Na2S04 and concentrated in vacuo. The crude material was purified by flash column chromatography on C18 (60 g). The column was eluted with MeCN:H20 + 0.1 % formic acid using the following gradient (% MeCN, column volumes): 10%, 2 CV; 10-40%, 10 CV; 40-100%, 2 CV; 100%, 2 CV. The desired fractions were combined and concentrated in vacuo to afford the product as a pale yellow foam (1.19 g, 60%). 1 H NMR (500 MHz, CD3OD) delta 8.40 (s, 1 H), 7.57 - 7.44 (m, 4H), 7.44 - 7.32 (m, 6H), 5.55 (s, 2H), 4.31 - 4.23 (m, 2H), 4.24 - 4.15 (m, 2H), 4.00 - 3.90 (m, 4H), 3.79 (dd, J = 9.4, 2.2 Hz, 2H), 3.64 (t, J = 10.5 Hz, 2H), 3.41 - 3.31 (m, 3H), 3.25 - 3.08 (m, 4H), 2.76 - 2.64 (m, 3H), 1.88 - 1.75 (m, 2H), 1.50 - 1.39 (m, 9H). LC/MS (System A): m/z (ESI+) = 693 [MH+], Rt = 0.94 min, ELS purity = 100%. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
20% | A mixture of <strong>[120278-07-1]benzyl 4-aminopiperidine-1-carboxylate</strong> (1.50 g, 6.40 mmol) and 4,6-0- benzylidene-D-glucopyranose (3.44 g, 12.8 mmol) in MeOH (40 ml) was stirred at RT for 2 h. AcOH (733 muIota, 12.8 mmol) was added, followed by portionwise addition of NaCNBH3 (805 mg, 12.8 mmol). The reaction was stirred at RT for 16 h. The reaction was recharged with 4,6-O-benzylidene-D-glucopyranose (3.44 g, 12.8 mmol) then the reaction was stirred at RT for a further 1 h. NaCNBH3 (805 mg, 12.8 mmol) was added then the reaction mixture was stirred at RT for a further 64 h. The reaction was recharged with AcOH (733 muIota, 12.8 mmol) then the reaction was stirred at RT for a further 4 h. 4,6-O-Benzylidene-D- glucopyranose (3.44 g, 12.8 mmol) was added then the reaction was stirred at RT for 0.5 h. AcOH (733 muIota, 12.8 mmol) and NaCNBH3 (805 mg, 12.8 mmol) were added then the reaction was left to stir at RT for a further 16 h. Saturated aqueous NaHCOs solution (20 ml) was added dropwise over 5 min. The resultant mixture was partitioned between EtOAc (60 ml) and saturated aqueous NaHCOs solution (50 ml). The phases were separated then the organic phase was washed with saturated aqueous NaHCOs solution (2 x 50 ml), water (2 x 50 ml), brine (20 ml), dried over Na2S04, filtered and evaporated to afford a white solid (4.8 g). The resultant solid was dissolved in MeOH:MeCN (1 : 1 , 10 ml) then half of the solution was retained crude for future purification whilst the other half was purified by flash column chromatography on C18 (60 g). The column was eluted with MeCN:water + 0.1 % NH4OH using the following gradient (%MeCN, column volumes): 5%, 2 CV; 5-23%, 4 CV; 23%, 3 CV; 23-49%, 5 CV; 49%, 2 CV; 49-100%, 10 CV; 100%, 2 CV. The desired fractions were combined and concentrated in vacuo to afford a white solid (1.39 g). The material thus obtained was further purified by flash column chromatography on C18 (12 g). The column was eluted with MeCN:water + 0.1 % formic acid using the following gradient (%MeCN, column volumes): 5%, 2 CV; 5-32%, 5 CV; 32%, 2 CV; 32-59%, 6 CV; 59-81 %, 1 CV, 100%, 1 CV. The desired fractions were combined and concentrated in vacuo to afford a white solid (1.12 g). The solid thus obtained was dissolved in EtOAc (50 ml) and extracted with saturated aqueous NaHC03 solution (2 x 20 ml) and water (10 ml), then dried over MgS04, filtered and evaporated to afford the product as a white solid (0.95 g, 20%). 1 H NMR (500 MHz, DMSO-cfe) delta 7.44 - 7.24 (m, 15H), 5.49 - 5.41 (m, 2H), 5.15 - 5.09 (m, 2H), 5.08 - 4.99 (m, 2H), 4.47 - 4.43 (m, 2H), 4.41 - 4.35 (m, 2H), 4.17 - 4.08 (m, 2H), 4.01 - 3.90 (m, 2H), 3.83 - 3.74 (m, 2H), 3.75 - 3.66 (m, 4H), 3.64 - 3.56 (m, 2H), 3.54 - 3.42 (m, 2H), 2.70 - 2.33 (m, 7H + DMSO), 1.72 - 1.59 (m, 2H), 1.39 - 1.27 (m, 1 H), 1.16 - 1.08 (m, 1 H). LC/MS (System A): m/z (ESI+) = 739 [MH+], Rt = 0.94 min, UV purity = 100%. |
Tags: 30688-66-5 synthesis path| 30688-66-5 SDS| 30688-66-5 COA| 30688-66-5 purity| 30688-66-5 application| 30688-66-5 NMR| 30688-66-5 COA| 30688-66-5 structure
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
Home
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :