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[ CAS No. 31053-99-3 ] {[proInfo.proName]}

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Cat. No.: {[proInfo.prAm]}
Chemical Structure| 31053-99-3
Chemical Structure| 31053-99-3
Structure of 31053-99-3 * Storage: {[proInfo.prStorage]}
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Product Details of [ 31053-99-3 ]

CAS No. :31053-99-3 MDL No. :MFCD28127502
Formula : C9H11Br Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 199.09 Pubchem ID :-
Synonyms :

Safety of [ 31053-99-3 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338 UN#:
Hazard Statements:H302-H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 31053-99-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 31053-99-3 ]

[ 31053-99-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 610-91-3 ]
  • [ 31053-99-3 ]
  • 2
  • [ 31053-99-3 ]
  • [ 767-77-1 ]
  • C18H23N [ No CAS ]
YieldReaction ConditionsOperation in experiment
With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene at 120℃; for 12h; Inert atmosphere; 1 1) In a 250 ml four-necked flask, under a nitrogen atmosphere, 0.03 mol of 2,3,5-trimethylaniline and 0.04 mol of 1-bromo-2,3,5-trimethylbenzene, 0.04mol of sodium tert-butoxide, 0.0015mol of Pd2(dba)3, 0.0015mol of tri-tert-butylphosphine, and 150ml of toluene were added, stirred and heated to 120°C. The reaction was refluxed for 12 hours. Samples were taken and the reaction was complete. The solution was naturally cooled and filtered. The filtrate was distilled under reduced pressure until no fractions were detected. A neutral silica column was used. Intermediate E1 was obtained, HPLC purity 90.49%, yield 62.30%.
With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene at 120℃; for 12h; Inert atmosphere; 1 1) 250ml four bottle,In a nitrogen atmosphere,Add 0.03 mol of 2,3,5-trimethylaniline,0.04 mol of compound 1-bromo-2,3,5-trimethylbenzene,0.04mol of sodium tert-butoxide,0.0015mol Pd2(dba)3,0.0015 mol of tri-tert-butylphosphine,150ml toluene, stirring and mixing,Heat to 120°C,Reflux reaction for 12 hours,Sampling point board,The reaction is completeNatural cooling,filter,The filtrate was evaporated under reduced pressure until no fractions were found.Over neutral silica gel column,Obtain the intermediate E1,Purity 90.49%,Yield 62.30%;
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