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Chemical Structure| 31081-59-1 Chemical Structure| 31081-59-1

Structure of Octadecyl methane sulfonate
CAS No.: 31081-59-1

Chemical Structure| 31081-59-1

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Synonyms: Octadecyl mesylate; Stearyl mesylate

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Product Details of [ 31081-59-1 ]

CAS No. :31081-59-1
Formula : C19H40O3S
M.W : 348.58
SMILES Code : CS(=O)(OCCCCCCCCCCCCCCCCCC)=O
Synonyms :
Octadecyl mesylate; Stearyl mesylate

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Application In Synthesis of [ 31081-59-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 31081-59-1 ]

[ 31081-59-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 623-57-4 ]
  • [ 31081-59-1 ]
  • [ 871258-14-9 ]
YieldReaction ConditionsOperation in experiment
4.5 g Sodium hydride (2.01 g, 50.4 mmol, 60percent in oil) was suspended in THF (20 ml) and 3-(dimethylamino)propane-1,2-diol (1.5 g, 12.6 mmol) in THF (10 mL) was added dropwise. The resulting solution was stirred for 10 min at RT and then a solution of methanesulfonic acid octadecyl ester (11.0 g, 31.5 mmol) in THF (40 mL) was added dropwise. The resulting reaction mixture was refluxed overnight. Then it was quenched with methanol and partitioned between diethyl ether and water. Organic layer was washed with brine and dried over anhydrous sodium sulfate. It was purified on silica gel by flash chromatography using methanol/methylene chloride. The title compound was isolated as yellowish oil which solidified upon standing (4.5 g). ES(+)-LRMS m/e calcd. for C41H85NO2 (M+H)+ 624.7, obsd. 624.8.
 

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