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Chemical Structure| 312612-62-7 Chemical Structure| 312612-62-7

Structure of 312612-62-7

Chemical Structure| 312612-62-7

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Product Details of [ 312612-62-7 ]

CAS No. :312612-62-7
Formula : C15H10IN
M.W : 331.15
SMILES Code : IC1=C(C2=CC=CC=C2)N=CC3=C1C=CC=C3

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Application In Synthesis of [ 312612-62-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 312612-62-7 ]

[ 312612-62-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 312612-62-7 ]
  • [ 37993-76-3 ]
YieldReaction ConditionsOperation in experiment
88% With zinc; In ethanol; for 12h;Inert atmosphere; Reflux; To a solution of 4-iodo-3-phenylisoquinoline (3A) (0.5 mmol,165.6 mg) in EtOH (7.5 mL) was added Zn powder (5.0 mmol,363.3 mg) under argon atmosphere. The obtained mixture wasstirred for 12 h at refluxing temperature. The cooled mixture wasfiltered through Celite, and then the filtrate was concentrated underreduced pressure. The residue was purified by column chromatographyon silica gel (eluent: n-hexane/AcOEt 4:1) to afford3-phenylisoquinoline (4A) (101.6 mg, 99%).
 

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